直接凝集试验及其他检测弓形虫抗体的检测方法。
Direct agglutination test and other assays for measuring antibodies to Toxoplasma gondii.
作者信息
Johnson J, Duffy K, New L, Holliman R E, Chessum B S, Fleck D G
机构信息
Public Health Laboratory Service, St George's Hospital, London.
出版信息
J Clin Pathol. 1989 May;42(5):536-41. doi: 10.1136/jcp.42.5.536.
Abstract
The performance of a direct agglutination test for the detection of toxoplasma specific IgG immunoglobulin was compared with that of the latex agglutination test. The direct agglutination test was less sensitive but more specific than the latex agglutination test. Quantitative results were not directly comparable, reflecting the different antibody profiles detected in each assay. The direct agglutination test represents an alternative to the latex agglutination test as a screening test for toxoplasmosis. Patients at risk of life threatening infection require detailed serological examination using additional assays.
摘要
将用于检测弓形虫特异性IgG免疫球蛋白的直接凝集试验的性能与乳胶凝集试验进行了比较。直接凝集试验的敏感性低于乳胶凝集试验，但特异性更高。定量结果无法直接比较，这反映了每种检测方法中检测到的不同抗体谱。直接凝集试验可作为弓形虫病筛查试验替代乳胶凝集试验。有危及生命感染风险的患者需要使用其他检测方法进行详细的血清学检查。
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