Department of Immunology, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Cell Host Microbe. 2011 Nov 17;10(5):423-5. doi: 10.1016/j.chom.2011.10.008.
Periodontitis is linked to polymicrobial interactions and the presence of Porphyromonas gingivalis. In this issue of Cell Host & Microbe, Hajishengallis et al. (2011) demonstrate that P. gingivalis colonization in the oral cavity changes the composition of the oral commensal microbiota and accelerates microbiota-mediated bone-destructive periodontitis, indicating that this single, low-abundance species is a keystone in periodontal disease.
牙周炎与多种微生物的相互作用和牙龈卟啉单胞菌的存在有关。在本期《细胞宿主与微生物》中，Hajishengallis 等人（2011 年）表明，口腔中牙龈卟啉单胞菌的定植会改变口腔共生菌群的组成，并加速菌群介导的破坏性牙周炎，这表明这种单一的低丰度物种是牙周病的关键。
