Güneş Alper, Konuk Şerife Gülhan, Demir Helin Deniz, Kurt Semiha, Naseri Erdinç, Erkorkmaz Ünal
School of Medicine, Department of Ophthalmology, Gaziosmanpaşa University, Tokat, Turkey.
School of Medicine, Department of Neurology, Gaziosmanpaşa University, Tokat, Turkey.
Int Ophthalmol. 2023 Feb;43(2):397-402. doi: 10.1007/s10792-022-02435-x. Epub 2022 Jul 21.
Coronary bypass surgery is emphasized in aetiology of ischemic optic neuropathy. Our aim in this study was to investigate the pattern visual evoked potentials (PVEP) in patients before and after coronary bypass surgery.
Thirty-one patients were included in the study. After a full ophthalmological evaluation, PVEP was assesed in the pre and postoperative periods. Operative times, hematological parameters, blood pressures, number of transfusions, body temperatures, anaesthetic drugs and systemic illnesses were recorded for each patient.
The mean age of the patients were 59 ± 10.4 years. There was 22 men and 9 women in the study. Only 3 of them needed transfusion during the surgery. The mean duration of the surgery was 3.2 ± 0.7 h. None of the patients had a history of visual disturbance or postoperative ischemic optic neuropathy. The mean VEP P100 amplitude was not statistically significantly different but the mean VEP P100 latency showed statistically significant difference between the preoperative and postoperative periods. (p = 0.014) This significance was more appereant in patients with systemic illnesses. (p = 0.023) There was a positive correlation between the age and VEP P100 latency (r = 0.402, p < 0.05).
Although surgical techniques and equipments are developing each day in the field of cardiopulmonary bypass surgery, the contributing factors such as hypothermia, anemia and diabetes still seem to affect neurophysiological functions even after a noncomplicated surgery.
冠状动脉搭桥手术在缺血性视神经病变的病因学中受到重视。本研究的目的是调查冠状动脉搭桥手术前后患者的图形视觉诱发电位（PVEP）。
31例患者纳入本研究。经过全面的眼科评估后，在术前和术后评估PVEP。记录每位患者的手术时间、血液学参数、血压、输血次数、体温、麻醉药物和全身疾病情况。
患者的平均年龄为59±10.4岁。本研究中有22名男性和9名女性。其中只有3人在手术期间需要输血。手术的平均持续时间为3.2±0.7小时。所有患者均无视力障碍病史或术后缺血性视神经病变。术前和术后期间，平均VEP P100波幅无统计学显著差异，但平均VEP P100潜伏期有统计学显著差异。（p = 0.014）这种差异在患有全身疾病的患者中更为明显。（p = 0.023）年龄与VEP P100潜伏期之间存在正相关（r = 0.402，p < 0.05）。
尽管体外循环心脏手术领域的手术技术和设备每天都在发展，但低温、贫血和糖尿病等影响因素即使在无并发症的手术后似乎仍会影响神经生理功能。
