Flemish Institute for Technological Research, Unit Environmental Health and Risk, Boeretang 200, 2400 Mol, Belgium.
Chemosphere. 2012 Jan;86(3):308-14. doi: 10.1016/j.chemosphere.2011.10.034. Epub 2011 Nov 21.
With the objective to evaluate exposure of the population in Flanders (Belgium) to perfluorinated compounds (PFCs), we measured perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) in settled dust in homes and offices, in a selection of food items from local origin, in drinking-water and in human serum. We complemented the data with results from a literature survey. Based on this dataset we calculated intake by children and adults from food, drinking-water, settled dust and soil, and air. Dietary exposure dominated overall intake. For adults, average dietary intake equalled 24.2 (P95 40.9) ng PFOS kg(-1) d(-1) and 6.1 (P95 9.6) ng PFOA kg(-1)d(-1), whereas for children the dietary intake was about 3 times higher. Predicted intake is high when compared to assessments in other countries, and to serum levels from Flanders, but comparable to the intakes published by The European Food Safety Authority (EFSA) in 2008. Intake of PFOS and PFOA remained below the Tolerable Daily Intake.
为了评估比利时佛兰德斯(Flanders)地区人群接触全氟化合物(PFCs)的情况,我们测量了家庭和办公室中沉降尘、当地来源的一些食物、饮用水和人血清中的全氟辛烷磺酸(PFOS)和全氟辛酸(PFOA)。我们用文献调查的结果补充了这些数据。基于该数据集,我们计算了儿童和成人通过食物、饮用水、沉降尘和土壤以及空气摄入这些物质的情况。饮食暴露是总摄入量的主要来源。对于成年人,平均饮食摄入量相当于 24.2(P95 40.9)ng PFOS/kg/d 和 6.1(P95 9.6)ng PFOA/kg/d,而儿童的摄入量约为成年人的 3 倍。与其他国家的评估以及与佛兰德斯的血清水平相比,预测的摄入量较高,但与欧洲食品安全局(EFSA)在 2008 年公布的摄入量相当。PFOS 和 PFOA 的摄入量仍低于每日耐受摄入量。