Epidemiology Department, Centre for Preventive Medicine, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk, UK.
Vet J. 2012 Jul;193(1):58-66. doi: 10.1016/j.tvjl.2011.10.020. Epub 2011 Nov 21.
Epidemiological studies into the risk factors for naturally-occurring equine laminitis are limited. There are a small number of such studies, although the results are inconsistent and remain disputed. The reasons for the conflicting results remain unclear. The aim of this review was to critically evaluate previous research in order to identify publications which provide the best evidence of risk factors for naturally-occurring equine laminitis. A systematic review of English language publications was conducted using MEDLINE (1950-2010), CAB Direct (1910-2010) and IVIS (1997-2010). Additional publications were included by searching bibliographies. Search terms included laminitis, equine, risk factors and epidemiology. Publications which compared a case population to a control population and made inferences about parameters as risk factors for naturally-occurring equine laminitis were included. Information was extracted using predefined data fields, including 18 study quality indicators. In total, 17 publications were fully appraised. Six were considered to provide the most reliable information about risk factors for naturally-occurring laminitis. Information on signalment was well researched and there was good evidence for an association with chronic laminitis and increasing age. There remain inconsistent results for many other horse-level risk factors including gender, breed and bodyweight. Previous publications estimating risk factors for equine laminitis were of reasonable quality, although they were limited in the number and scope of the risk factors studied. High-quality, evidence-based studies are needed to identify further risk factors and to establish consensus over previously identified risk factors for different equine populations.
关于自然发生的马属动物蹄叶炎的风险因素的流行病学研究很有限。尽管有少数此类研究，但结果不一致且仍存在争议。冲突结果的原因尚不清楚。本综述的目的是批判性地评估以前的研究，以确定提供自然发生的马属动物蹄叶炎风险因素的最佳证据的出版物。使用 MEDLINE（1950-2010 年）、CAB Direct（1910-2010 年）和 IVIS（1997-2010 年）进行了英语出版物的系统评价。通过搜索参考文献，包括了其他出版物。搜索词包括蹄叶炎、马、风险因素和流行病学。包括将病例人群与对照人群进行比较并推断参数作为自然发生的马属动物蹄叶炎的风险因素的出版物。使用预定义的数据字段提取信息，包括 18 个研究质量指标。总共评估了 17 篇完整的出版物。其中 6 篇被认为提供了有关自然发生蹄叶炎风险因素的最可靠信息。关于品种特征的信息研究得很好，并且有证据表明与慢性蹄叶炎和年龄增长有关。许多其他与马相关的风险因素，包括性别、品种和体重，仍然存在不一致的结果。以前发表的估计马属动物蹄叶炎风险因素的出版物质量合理，尽管它们研究的风险因素数量和范围有限。需要高质量的循证研究来确定进一步的风险因素，并在不同的马属动物群体中就先前确定的风险因素达成共识。
