Bernersen B, Johnsen R, Straume B, Burhol P G, Jenssen T G, Stakkevold P A
Department of Medicine, University Hospital of Tromsø, Norway.
Gut. 1990 Sep;31(9):989-92. doi: 10.1136/gut.31.9.989.
This study, designed to overcome methodological problems inherent in earlier prevalence studies of peptic ulcer, was carried out in a municipality in northern Norway. It included the total population of 2027, aged 20-69 years, and comprised a questionnaire and search for previously diagnosed peptic ulcers in the local medical records for all subjects, and additional endoscopy of all subjects with dyspepsia and their matched healthy controls (n = 619). The overall prevalence was 10.5% in men and 9.5% in women, a sex ratio close to one and a higher duodenal:gastric ratio than previously reported from this region. A substantial 1% prevalence of asymptomatic ulcers was also observed.
本研究旨在克服早期消化性溃疡患病率研究中固有的方法学问题,在挪威北部的一个自治市开展。研究涵盖了2027名年龄在20至69岁之间的全部人口,包括一份问卷调查,并在当地医疗记录中查找所有受试者先前诊断的消化性溃疡,此外还对所有消化不良受试者及其匹配的健康对照(n = 619)进行了内镜检查。总体患病率男性为10.5%,女性为9.5%,性别比接近1,十二指肠溃疡与胃溃疡的比例高于该地区先前报告的比例。还观察到无症状溃疡的患病率高达1%。