Geological Survey of Finland (GTK), P.O. Box 1237, Neulaniementie 5, FI-70211 Kuopio, Finland.
Environ Res. 2012 Jan;112:126-8. doi: 10.1016/j.envres.2011.11.001. Epub 2011 Nov 20.
The incidence of type 2 diabetes is increasing among Finnish young adults. A slightly increased risk in men was found in the north-east and western part of the country. The higher risk areas in women were found in the western coastal area and in eastern Finland. The present register-based study aimed to evaluate the regional association of the incidence of type 2 diabetes among young adults with the concentration of magnesium in local ground water. The association was evaluated using Bayesian modeling of geo-referenced data aggregated into a regular 10 km × 10 km grid cells. No marked association was found, although suggestive findings were detected for magnesium in well water and diabetes in young adult women. The results of this register-based study did not completely rule out the association of well water magnesium with the geographical variation of type 2 diabetes. The incidence of type 2 diabetes was much higher among individuals aged 40 or over. These suggestive findings indicate that the association between magnesium and type 2 diabetes would also be worth examining among individuals over 40 years of age.
芬兰年轻人中 2 型糖尿病的发病率正在上升。在该国东北部和西部地区，男性的风险略高。在女性中，高风险地区位于西部沿海地区和芬兰东部。本基于登记的研究旨在评估 2 型糖尿病在年轻人中的发病率与当地地下水镁浓度之间的区域相关性。使用贝叶斯建模对地理参考数据进行评估，将其汇总到规则的 10km×10km 网格单元中。没有发现明显的相关性，尽管在井水镁和年轻成年女性糖尿病方面发现了提示性结果。本基于登记的研究结果并未完全排除井水镁与 2 型糖尿病地理变异之间的关联。40 岁及以上个体的 2 型糖尿病发病率要高得多。这些提示性发现表明，在 40 岁以上人群中，镁与 2 型糖尿病之间的关联也值得研究。
