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[老年医学中的复方药物。该特殊年龄组进行临床研究的必要性]

[Combination drugs in geriatrics. The need for clinical studies in this special age group].

作者信息

Platt D

机构信息

Lehrstuhl für Innere Medizin, Universität Erlangen-Nürnberg.

出版信息

Fortschr Med. 1990 Aug 30;108(25):482-4.

PMID:2210585
Abstract

Multimorbidity frequently prompts the use of multiple drugs with the aim of treating the individual diseases simultaneously. Ingestion of a number of different drugs incurs the risk of early and more frequent side effects, as well as interactions between the various drugs. There is a tendency among patients of all age groups, intentional or unintentional not to take their medication. Among elderly patients regular compliance is a special problem. Reduction of the high consumption of drugs by the elderly is possible by therapy with combination drugs. The present paper discusses the advantages and disadvantages.

摘要

多种疾病共存常常促使人们同时使用多种药物来治疗各种疾病。服用多种不同药物会带来早期和更频繁出现副作用的风险,以及各种药物之间的相互作用。所有年龄段的患者都存在有意或无意不遵医嘱服药的倾向。在老年患者中,定期遵医嘱服药是一个特别的问题。通过联合用药治疗可以减少老年人的高药物消费量。本文讨论了其优缺点。

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