Rosholm J U, Bjerrum L, Hallas J, Worm J, Gram L F
Department of Clinical Pharmacology, IMB, Odense University Hospital.
Dan Med Bull. 1998 Apr;45(2):210-3.
To analyze the use of all subsidized prescription drugs with special attention to the elderly (> or = 70 years of age), including their use of drug combination generally accepted as carrying a risk of severe interactions.
Descriptive prevalence study.
Odense Pharmacoepidemiological Database, Denmark. The fourth quarter of 1994.
All inhabitants in the county of Funen, Denmark.
Prevalence of drug use for persons < 70 and > or = 70 years of age including number of drugs used and of drug combinations. Occurrence of 45 drug combinations generally accepted as carrying a risk of severe interactions.
Among persons less than 70 years, 67.9% used none, 16.5% used one drug and 15.6% used two or more prescription drugs. The corresponding prevalences for the elderly were 35.7%, 15.9% and 48.4%. The 26,337 elderly patients with at least two drugs used 21,293 different combinations. Of the elderly patients who had purchased > or = two drugs, 4.4% had combinations of drugs carrying a risk of severe interactions.
Most elderly use drugs and usually several drugs concomitantly. The elderly form a heterogeneous group of drug users. Drug combinations carrying a risk of severe interactions are relatively frequent.
分析所有补贴处方药的使用情况，特别关注老年人（≥70岁），包括他们使用通常被认为有严重相互作用风险的药物组合的情况。
描述性患病率研究。
丹麦欧登塞药物流行病学数据库。1994年第四季度。
丹麦菲英岛县的所有居民。
年龄<70岁和≥70岁人群的药物使用患病率，包括使用药物的数量和药物组合情况。45种通常被认为有严重相互作用风险的药物组合的出现情况。
在70岁以下人群中，67.9%未使用任何药物，16.5%使用一种药物，15.6%使用两种或更多种处方药。老年人的相应患病率分别为35.7%、15.9%和48.4%。26337名至少使用两种药物的老年患者使用了21293种不同的组合。在购买了≥两种药物的老年患者中，4.4%的患者使用了有严重相互作用风险的药物组合。
大多数老年人使用药物，通常同时使用几种药物。老年人是一个用药情况各异的群体。有严重相互作用风险的药物组合相对常见。
