Program in Physical Therapy, Washington University School of Medicine, St. Louis, MO, USA.
PM R. 2011 Nov;3(11):1055-1067.e1. doi: 10.1016/j.pmrj.2011.08.533.
Hip osteoarthritis (OA) leads to significant functional limitations and economic burden. If modifiable risk factors for hip OA are identified, it may be possible to implement preventative measures. Bony abnormalities associated with acetabular dysplasia (AD) and femoroacetabular impingement have been recently implicated as risk factors for hip OA. The purpose of this focused review is to summarize the available evidence describing the relationship between bony abnormalities and hip OA. A librarian-assisted database search with PubMed, Embase, and CENTRAL was performed. Relevant articles were identified and assessed for inclusion criteria. The authors reviewed cohort and case-control studies that reported on the association between abnormal hip morphology and hip OA. The available literature suggests that an association exists between bony abnormalities found in AD and femoroacetabular impingement and hip OA, and preliminary evidence suggests that AD is a risk factor for OA; however, these conclusions are based on limited evidence. Prospective, longitudinal studies are needed to confirm the causal relationship between abnormal hip morphology and the future development of hip OA.
髋骨骨关节炎(OA)导致严重的功能受限和经济负担。如果能确定髋骨 OA 的可修正风险因素,就有可能采取预防措施。与髋臼发育不良(AD)和股骨髋臼撞击症相关的骨异常最近被认为是髋骨 OA 的危险因素。本重点综述旨在总结现有证据,描述骨异常与髋骨 OA 之间的关系。在 PubMed、Embase 和 CENTRAL 数据库中进行了图书馆员辅助的数据库搜索。确定了相关文章,并评估了其纳入标准。作者回顾了报告髋形态异常与髋骨 OA 之间关系的队列研究和病例对照研究。现有文献表明,AD 和股骨髋臼撞击症中发现的骨异常与髋骨 OA 之间存在关联,初步证据表明 AD 是 OA 的一个危险因素;然而,这些结论是基于有限的证据。需要进行前瞻性、纵向研究来确认髋形态异常与未来髋骨 OA 发展之间的因果关系。