Department of Medical Statistics and Epidemiology, Sun Yat-Sen University, Guangdong, China.
Biomed Environ Sci. 2011 Aug;24(4):349-56. doi: 10.3967/0895-3988.2011.04.005.
Since HFMD was designated as a class C communicable disease in May 2008, 18 months surveillance data have been accumulated to December 2009. This article was to describe the distribution of HFMD for age, sex, area, and time between 2008 and 2009, to reveal the characteristics of the epidemic.
We analyzed weekly reported cases of HFMD from May 2008 to December 2009, and presented data on the distribution of age, sex, area and time. A discrete Poisson model was used to detect spatial-temporal clusters of HFMD.
More than 1 065 000 cases of HFMD were reported in Mainland China from May 2008 to December 2009 (total incidence: 12.47 per 10 000). Male incidence was higher than female for all ages and 91.9% of patients were <5 years old. The incidence was highest in Beijing, Shanghai, Zhejiang and Hainan. The highest peak of HFMD cases was in April and the number of cases remained high from April to August. The spatial-temporal distribution detected four clusters.
Children <5 years old were susceptible to HFMD and we should be aware of their vulnerability. The incidence was higher in urban than rural areas, and an annual pandemic usually starts in April.
自 2008 年 5 月将手足口病（HFMD）列为丙类传染病以来，截至 2009 年 12 月已积累了 18 个月的监测数据。本文描述了 2008 年至 2009 年期间 HFMD 的年龄、性别、地区和时间分布，揭示了该病的流行特征。
我们分析了 2008 年 5 月至 2009 年 12 月每周报告的 HFMD 病例，并展示了年龄、性别、地区和时间分布的数据。采用离散泊松模型检测 HFMD 的时空聚集性。
中国大陆 2008 年 5 月至 2009 年 12 月共报告手足口病超过 106.5 万例（总发病率：每 10 000 人 12.47 例）。各年龄段男性发病率均高于女性，91.9%的患者年龄<5 岁。发病率最高的地区为北京、上海、浙江和海南。HFMD 病例的最高峰值出现在 4 月，4 月至 8 月病例数居高不下。时空分布检测到 4 个聚集区。
<5 岁的儿童易患 HFMD，应注意其易感性。城市地区发病率高于农村地区，每年的流行期通常从 4 月开始。
