Irvine3 Labs, Department of Biomedical Sciences Chieti - Pescara University, Pescara, Italy.
Panminerva Med. 2011 Sep;53(3 Suppl 1):75-82.
This study compared the effects of supplementation with Pycnogenol® on cognitive function, attention and mental performance in students with an 8 week, evaluation study. Pycnogenol® was used in healthy students; the supplement was used with the aim of enhancing "normal" mental performances.
Attention, memory, evaluation of executive functions were included and students were also evaluated - in the 8-week study - according to results of the university tests. Fifty-three students (range 18-27 years) were included and Pycnogenol® was administered for 8 weeks. A group of equivalent students were followed up as a control group.
In the 8-week study Pycnogenol® supplementation improved sustained attention, memory, executive functions and mood ratings in the students. The improvement was statistically significant. The actual performance on real tests was measured in students undergoing university examinations. The controls failed 9 tests out a total of 84 (10.71%). In the Pycnogenol® group the students failed 7 tests out of 112 (6.25%) with a difference of 4.46% of failures in the Pycnogenol® group that performed, statistically, generally better. The average test score measured by the marks obtained was 23.81 (1.1) in controls vs. 26.1(1.3) (P<0.024) in the Pycnogenol® group (+2.29 equivalent to 7.6%).
This study indicates a role for Pycnogenol® to improve cognitive function in normal students.
本研究比较了补充碧萝芷®对 8 周评估研究中具有认知功能、注意力和精神表现的学生的影响。碧萝芷®用于健康学生；该补充剂旨在增强“正常”的精神表现。
包括注意力、记忆力、执行功能评估，学生还根据大学考试的结果在 8 周研究中进行评估。共有 53 名学生（年龄 18-27 岁）参与了研究，并接受了 8 周的碧萝芷®治疗。一组同等数量的学生作为对照组进行随访。
在 8 周的研究中，碧萝芷®补充剂改善了学生的持续注意力、记忆力、执行功能和情绪评分。改善具有统计学意义。实际的考试表现是通过参加大学考试的学生来衡量的。对照组在总共 84 次考试中有 9 次失败（10.71%）。在碧萝芷®组中，学生在 112 次考试中有 7 次失败（6.25%），差异为 4.46%，表明碧萝芷®组的表现总体上更好。通过所获得的分数衡量的平均考试成绩在对照组为 23.81（1.1），在碧萝芷®组为 26.1（1.3）（P<0.024），增加了 2.29 等效于 7.6%）。
本研究表明碧萝芷®在改善正常学生认知功能方面具有作用。
