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少数民族人群中心力衰竭和心房颤动的患病率:英格兰种族超声心动图筛查研究(E-ECHOES)。

Prevalence of heart failure and atrial fibrillation in minority ethnic subjects: the Ethnic-Echocardiographic Heart of England Screening Study (E-ECHOES).

机构信息

Primary Care Clinical Sciences, University of Birmingham, Birmingham, United Kingdom.

出版信息

PLoS One. 2011;6(11):e26710. doi: 10.1371/journal.pone.0026710. Epub 2011 Nov 16.

Abstract

BACKGROUND

Limited data exists on the prevalence of heart failure amongst minority groups in the UK. To document the community prevalence and severity of left ventricular systolic dysfunction, heart failure, and atrial fibrillation, amongst the South Asian and Black African-Caribbean groups in the UK.

METHODS AND RESULTS

We conducted a cross-sectional study recruiting from September 2006 to July 2009 from 20 primary care centres in Birmingham, UK. 10,902 eligible subjects invited, 5,408 participated (49.6%) and 5,354 had complete data (49.1%). Subjects had median age 58.2 years (interquartile range 51.0 to 70.0), and 2544 (47.5%) were male. Of these, 1933 (36.3%) had BMI>30 kg/m(2), 1,563 (29.2%) had diabetes, 2676 (50.0%) had hypertension, 307 (5.7%) had a history of myocardial infarction, and 104 (1.9%) had history of arrhythmia. Overall, 59 (1.1%) had an Ejection Fraction<40%, and of these 40 (0.75%) were NYHA class ≥2; 51 subjects (0.95%) had atrial fibrillation. Of the remaining 19 patients with an EF<40%, only 4 patients were treated with furosemide. A further 54 subjects had heart failure with preserved ejection fraction.

CONCLUSIONS

This is the largest study of the prevalence of left ventricular systolic dysfunction, heart failure and atrial fibrillation in under-researched minority communities in the UK. The prevalence of heart failure in these minority communities appears comparable to that of the general population but less than anticipated given the high rates of cardiovascular disease in these groups. Heart failure continues to be a major cause of morbidity in all ethnic groups and preventive strategies need to be identified and implemented.

摘要

背景

英国少数民族群体中心力衰竭的患病率数据有限。为了记录英国南亚和非裔加勒比人群体中左心室收缩功能障碍、心力衰竭和心房颤动的社区患病率和严重程度。

方法和结果

我们进行了一项横断面研究,于 2006 年 9 月至 2009 年 7 月在英国伯明翰的 20 个初级保健中心招募参与者。共邀请了 10902 名符合条件的受试者,其中 5408 名(49.6%)参与,5354 名(49.1%)完成了完整的数据收集。受试者的中位年龄为 58.2 岁(四分位间距为 51.0 至 70.0),2544 名(47.5%)为男性。其中,1933 名(36.3%)的 BMI>30kg/m²,1563 名(29.2%)患有糖尿病,2676 名(50.0%)患有高血压,307 名(5.7%)有心肌梗死病史,104 名(1.9%)有心律失常病史。总体而言,59 名(1.1%)的射血分数<40%,其中 40 名(0.75%)为 NYHA 分级≥2 级;51 名受试者(0.95%)患有心房颤动。在其余 19 名射血分数<40%的患者中,仅有 4 名患者接受了呋塞米治疗。另有 54 名患者患有射血分数保留的心力衰竭。

结论

这是在英国研究人数较少的少数民族群体中心力衰竭、心力衰竭和心房颤动患病率的最大规模研究。这些少数民族社区中心力衰竭的患病率与一般人群相当,但考虑到这些人群中心血管疾病的高发病率,预期患病率会更低。心力衰竭仍然是所有族裔群体发病率的主要原因,需要确定并实施预防策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a86/3217919/f94df8bbebf0/pone.0026710.g001.jpg

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