Imamoto Takashi, Goto Yusuke, Utsumi Takanobu, Fuse Miki, Kawamura Koji, Kamiya Naoto, Naya Yukio, Suzuki Hiroyoshi, Kondo Yukihiro, Ichikawa Tomohiko
Department of Urology, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.
Prostate Cancer. 2011;2011:606505. doi: 10.1155/2011/606505. Epub 2011 Jul 14.
Objective. The aim of the present study was to evaluate initial learning curves of laparoscopic radical prostatectomy (LRP) with regard to complications, urinary continence, and oncologic outcome. Materials and Methods. We retrospectively reviewed 100 consecutive patients with clinically localized prostate cancer. All 100 patients underwent LRP performed by the same urologist at one institution.
Mean operating time (208.4 ± 48.6 min), estimated blood loss (495.8 ± 436.5 mL), allogeneic blood transfusion rate (0%), and intraoperative complications diminished with surgical experience. Positive margin rate varied greatly among pathological stage (positive margin rates: pT2 = 20.5%; pT3 = 63.0%). A trend towards reduction of positive surgical margins in pT2 cases was apparent with increasing experience. Intraoperative and early complications occurred in 2.0% of patients. In all patients, 85.9% used none or no more than one pad per 24 h at 6 months postoperatively. Prostate-specific antigen recurrence was seen in only 2 patients. Conclusions. In the present series of 100 patients, our retrospective evaluation confirms that LRP provides satisfactory results.
目的。本研究的目的是评估腹腔镜根治性前列腺切除术（LRP）在并发症、尿失禁和肿瘤学结果方面的初始学习曲线。材料与方法。我们回顾性分析了100例连续的临床局限性前列腺癌患者。所有100例患者均在同一机构由同一位泌尿外科医生进行LRP手术。
平均手术时间（208.4±48.6分钟）、估计失血量（495.8±436.5毫升）、异体输血率（0%）以及术中并发症随着手术经验的增加而减少。切缘阳性率在不同病理分期中差异很大（切缘阳性率：pT2=20.5%；pT3=63.0%）。随着经验的增加，pT2病例中手术切缘阳性率有下降趋势。2.0%的患者发生了术中及早期并发症。所有患者中，85.9%在术后6个月时每24小时使用不超过一片或不用尿垫。仅2例患者出现前列腺特异性抗原复发。结论。在本系列100例患者中，我们的回顾性评估证实LRP提供了满意的结果。
