Yates Jennifer, Munver Ravi, Sawczuk Ihor
Department of Urology, Hackensack University Medical Center, 360 Essex Street, Hackensack, NJ 07601, USA.
Prostate Cancer. 2011;2011:618623. doi: 10.1155/2011/618623. Epub 2010 Nov 29.
Introduction. Obesity and prostate cancer are among the more common health issues affecting men in the United States. Methods. We retrospectively reviewed morbidly obese (BMI ≥ 40 kg/m(2)) patients undergoing RALP between 2004-2009 at our institution. Parameters including operative time, estimated blood loss, hospital stay, pathology, and complication rate were examined. Results. A total of 15 patients were included, with a mean BMI of 43 kg/m(2). Mean preoperative PSA was 5.78 ng/dL, and Gleason score was 6.6. Mean operative time was 163 minutes, and mean estimated blood loss was 210 mL. The mean hospital stay was 1.3 days. Positive margins were noted in 2 (13%) patients, each with pT3 disease. There were no blood transfusions, open conversions, or Clavien Grade II or higher complications. Conclusions. In our experience, RALP is feasible in morbidly obese patients. We noted several challenges in this patient population which were overcome with modification of technique and experience.
引言。肥胖症和前列腺癌是影响美国男性的较为常见的健康问题。方法。我们回顾性研究了2004年至2009年间在我院接受机器人辅助腹腔镜前列腺切除术(RALP)的病态肥胖(体重指数≥40kg/m²)患者。对包括手术时间、估计失血量、住院时间、病理和并发症发生率等参数进行了检查。结果。共纳入15例患者,平均体重指数为43kg/m²。术前平均前列腺特异抗原(PSA)为5.78ng/dL, Gleason评分6.6。平均手术时间为163分钟,平均估计失血量为210mL。平均住院时间为1.3天。2例(13%)患者切缘阳性,均为pT3期疾病。无输血、转为开放手术或Clavien二级及以上并发症。结论。根据我们的经验,机器人辅助腹腔镜前列腺切除术在病态肥胖患者中是可行的。我们注意到该患者群体存在一些挑战,通过技术改进和经验积累得以克服。