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气管内吸痰对危重症成年患者混合静脉血氧饱和度及心率的影响

Effects of endotracheal suctioning on mixed venous oxygen saturation and heart rate in critically ill adults.

作者信息

Clark A P, Winslow E H, Tyler D O, White K M

机构信息

School of Nursing, University of Texas, Austin 78701.

出版信息

Heart Lung. 1990 Sep;19(5 Pt 2):552-7.

PMID:2211166
Abstract

The purpose of this multisite study was to determine the effects of endotracheal suctioning on mixed venous oxygen saturation (SvO2) and heart rate in 189 critically ill adults. One-pass, intermittent suction was applied for 10 or fewer seconds, with three prehyperoxygenation and three posthyperoxygenation breaths of 100% oxygen. Subjects at three hospitals (n = 127) underwent suctioning using hyperoxygenation with anesthesia bags and traditional suction catheters (open suction method). Subjects at one hospital (n = 62) underwent suctioning with hyperoxygenation by ventilator and in-line suction catheters (closed suction method). For subjects from all hospital sites combined, the SvO2 decreased from 67% to 64% (p = 0.001), a 4% change from baseline, and returned to baseline within 2 minutes. However, in subjects receiving the open method of suction, SvO2 dropped from 66% to 62% immediately after suctioning and returned to baseline within 4 minutes. In contrast, when the closed suction method was used, SvO2 rose from 67.7% to 67.86% immediately after suctioning, drifting upward to 71% for the next 2 minutes before dropping toward the baseline after 4 minutes. Mean heart rate increased from a baseline of 99 beats/min to 104 beats/min immediately after suctioning (p = 0.001), a 5% change from baseline, and gradually returned to baseline over the next 4 minutes. No significant differences were seen in heart rate between subjects having the open versus closed suction method. In conclusion, the closed suction method showed a higher SvO2 after endotracheal suctioning compared with the open suction method (p = 0.0001). Some form of hyperoxygenation before and after endotracheal suctioning is recommended.

摘要

这项多中心研究的目的是确定气管内吸痰对189名危重症成年患者的混合静脉血氧饱和度(SvO2)和心率的影响。采用单次、间歇性吸痰,持续10秒或更短时间,吸痰前后各进行3次100%氧气的预充氧和后充氧呼吸。三家医院的127名受试者使用麻醉袋和传统吸痰导管进行充氧吸痰(开放吸痰法)。一家医院的62名受试者通过呼吸机和内置吸痰导管进行充氧吸痰(密闭吸痰法)。对于所有医院的受试者,SvO2从67%降至64%(p = 0.001),较基线变化4%,并在2分钟内恢复到基线水平。然而,采用开放吸痰法的受试者,吸痰后SvO2立即从66%降至62%,并在4分钟内恢复到基线水平。相比之下,采用密闭吸痰法时,吸痰后SvO2立即从67.7%升至67.86%,在接下来的2分钟内上升至71%,4分钟后降至基线水平。平均心率从基线的99次/分钟立即升至吸痰后的104次/分钟(p = 0.001),较基线变化5%,并在接下来的4分钟内逐渐恢复到基线水平。开放吸痰法与密闭吸痰法受试者的心率无显著差异。总之,与开放吸痰法相比,密闭吸痰法在气管内吸痰后SvO2更高(p = 0.0001)。建议在气管内吸痰前后采用某种形式的充氧。

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