Division of Gastroenterology, Hepatology and Nutrition, British Columbia Childrens Hospital, Vancouver, BC, Canada.
Paediatr Drugs. 2012 Apr 1;14(2):79-89. doi: 10.2165/11594360-000000000-00000.
Gastroesophageal reflux (GER) is a common presenting complaint in children and adults, and is a frequent reason for physician consultation. GER disease (GERD), whilst benign in the majority of cases, is frequently a chronic condition that has been shown to result in significantly reduced quality of life in children and adolescents. Furthermore, there is emerging evidence that the prevalence of GERD is rising and may have links to adult obesity and other morbidities. Consequently, accurate diagnosis, appropriate management strategies, and timely referral to specialist services are important principles in the effective management of GERD. Acid-suppressive drugs are effective therapies but are one of the most costly classes of drugs prescribed. Therefore, not only is an accurate diagnosis important to the patient, but it is also of significant interest from a public health and resource utilization standpoint.
胃食管反流（GER）是儿童和成人常见的主诉，也是医生就诊的常见原因。胃食管反流病（GERD）虽然在大多数情况下是良性的，但常常是一种慢性疾病，已被证明会显著降低儿童和青少年的生活质量。此外，有新的证据表明，GERD 的患病率正在上升，并且可能与成人肥胖和其他疾病有关。因此，准确的诊断、适当的管理策略以及及时转介给专科服务是 GERD 有效管理的重要原则。抑酸药物是有效的治疗方法，但也是处方中最昂贵的药物类别之一。因此，不仅准确的诊断对患者很重要，从公共卫生和资源利用的角度来看，这也是非常重要的。
