Whitworth J A, Coghlan J P, Denton D A, Hardy K J, Scoggins B A
Cardiovasc Res. 1979 Jan;13(1):9-15. doi: 10.1093/cvr/13.1.9.
Sodium chloride loading produced a rise in blood pressure in intact sheep which was potentiated by reduction in renal mass. ACTH induced hypertension was also potentiated by reduced renal mass, suggesting a volume component for the hypertension when renal excretory capacity for salt and water is reduced.
给完整的绵羊输注氯化钠会使其血压升高,而肾质量减少会增强这种作用。促肾上腺皮质激素诱导的高血压也会因肾质量减少而增强,这表明当肾脏对盐和水的排泄能力降低时,高血压存在容量因素。