Section of Oral and Maxillofacial Surgery, Division of Maxillofacial Diagnostic and Surgical Sciences, Graduate School of Dental Science, Kyushu University, Fukuoka, Japan.
Int J Oral Maxillofac Surg. 2012 Mar;41(3):290-6. doi: 10.1016/j.ijom.2011.10.015. Epub 2011 Nov 22.
The purpose of this study was to determine how keratocystic odontogenic tumours (KCOTs) in the mandible are reduced during marsupialisation, and to predict the best time for secondary enucleation by analysing computed tomography (CT) images. 15 patients with KCOTs were treated with marsupialisation surgery, and 42 series of CT data taken during the marsupialisation process were analysed. CT data were reconstructed in three-dimensional (3D) images. The 3D images were used to measure the diameter and volume, and to analyse the changes that occurred after marsupialisation. Marsupialised KCOTs tended to be reduced equally towards the window in the tumour. The amount of volume reduction per day (V(r)) was reduced in proportion to the volume (V) with the formula V(r)=-0.0029×V. The formula manipulation for V was V=V(0)×e(-0.0029t) (t=duration after marsupialisaton (day)). The volume of marsupialised KCOTs was reduced by half over a 239 day cycle. These results demonstrate that the future shape of marsupialised mandibular KCOTs, under good control, could be predicted with significant accuracy using CT data. This prediction could decrease the prolonged marsupialisation state in patients with KCOTs.
本研究旨在探讨颌骨角化囊性瘤（KCOT）在经袋形手术后如何缩小，并通过分析 CT 图像预测二次剜除的最佳时机。15 例 KCOT 患者接受了袋形手术治疗，对手术过程中的 42 组 CT 数据进行了分析。对 CT 数据进行三维（3D）重建。使用 3D 图像测量直径和体积，并分析袋形术后的变化。经袋形化处理后的 KCOT 肿瘤向开窗处均匀缩小。体积减少量（V(r)）与体积（V）呈比例减少，公式为 V(r)=-0.0029×V。V 的公式为 V=V(0)×e(-0.0029t)（t= 袋形术后时间（天））。KCOT 经袋形化治疗 239 天后体积减少一半。这些结果表明，通过 CT 数据可以非常准确地预测受良好控制的颌骨 KCOT 袋形化后的未来形态。这一预测可以减少 KCOT 患者的长期袋形化状态。
