• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

牙源性角化囊肿治疗中减压后摘除术的临床及组织形态计量学评估

Clinical and histomorphometric evaluation of decompression followed by enucleation in the treatment of odontogenic keratocyst.

作者信息

Oh Ji-Su, You Jae-Seek, Kim Su-Gwan

机构信息

Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea.

出版信息

J Dent Sci. 2018 Dec;13(4):329-333. doi: 10.1016/j.jds.2018.06.001. Epub 2018 Jun 18.

DOI:10.1016/j.jds.2018.06.001
PMID:30895141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6388872/
Abstract

BACKGROUND/PURPOSE: The classification and treatment of odontogenic keratocyst (OKC) are controversial. The objective of this study was to present the efficiency of decompression followed by enucleation by clinical and histomorphometric evaluation for the treatment of OKC.

MATERIALS AND METHODS

Thirty four OKCs of 27 patients who underwent decompression followed by enucleation were included in this study. Clinical and histomorphometric analysis were performed.

RESULTS

The average decreasing rate was 59% in maximum diameter, 66% in the amount of the volume for the average of period of the decompression was 9.8 months. The mean of increasing rate of the thickness of the epithelial lining was 921.16%. There were no recurrences for a mean follow-up period of 5.8 years. The thin and friable cyst wall of the OKC was changed to thickened, hard type.

CONCLUSION

The decompression was found to be effective and reliable as a treatment of the OKC to decrease the recurrence tendency, even for Gorlin-Goltz syndrome.

摘要

背景/目的：牙源性角化囊肿（OKC）的分类和治疗存在争议。本研究的目的是通过临床和组织形态计量学评估，呈现减压后摘除术治疗OKC的疗效。

材料与方法

本研究纳入了27例接受减压后摘除术的患者的34个OKC。进行了临床和组织形态计量学分析。

结果

减压平均时长为9.8个月，最大直径平均减小率为59%，体积平均减小率为66%。上皮衬里厚度的平均增加率为921.16%。平均随访5.8年无复发。OKC薄而脆的囊壁转变为增厚、坚硬型。

结论

减压作为一种治疗OKC的方法，被发现是有效且可靠的，可降低复发倾向，即使对于戈林-戈尔茨综合征患者也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/5dcdd926e6db/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/1bc613b54ea4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/f1bbd903b413/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/e7113904d313/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/7fee3f78243d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/5dcdd926e6db/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/1bc613b54ea4/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/f1bbd903b413/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/e7113904d313/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/7fee3f78243d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/5dcdd926e6db/gr5.jpg

相似文献

1
Clinical and histomorphometric evaluation of decompression followed by enucleation in the treatment of odontogenic keratocyst.牙源性角化囊肿治疗中减压后摘除术的临床及组织形态计量学评估
J Dent Sci. 2018 Dec;13(4):329-333. doi: 10.1016/j.jds.2018.06.001. Epub 2018 Jun 18.
2
Fourteen-year study of the management of the odontogenic keratocyst. Are adjunctive therapies all they are cut out to be?牙源性角化囊肿治疗的十四年研究。辅助治疗是否名副其实？
Br J Oral Maxillofac Surg. 2022 Feb;60(2):105-112. doi: 10.1016/j.bjoms.2021.01.021. Epub 2021 Apr 1.
3
Conservative surgical treatments for nonsyndromic odontogenic keratocysts: a systematic review and meta-analysis.非综合征性牙源性角化囊肿的保守手术治疗：系统评价和荟萃分析。
Clin Oral Investig. 2018 Jun;22(5):2089-2101. doi: 10.1007/s00784-017-2315-8. Epub 2017 Dec 20.
4
Odontogenic keratocyst: to decompress or not to decompress? A comparative study of decompression and enucleation versus resection/peripheral ostectomy.牙源性角化囊肿：减压还是不减压？减压与摘除术及切除/周边骨切除术的对比研究
J Oral Maxillofac Surg. 2007 Apr;65(4):640-4. doi: 10.1016/j.joms.2006.06.284.
5
The recurrence of odontogenic keratocysts in pediatric patients is associated with clinical findings of Gorlin-Goltz Syndrome.牙源性角化囊肿在儿科患者中的复发与 Gorlin-Goltz 综合征的临床特征有关。
Med Oral Patol Oral Cir Bucal. 2020 Jan 1;25(1):e56-e60. doi: 10.4317/medoral.23185.
6
Gorlin-Goltz Syndrome: A Case Series.戈林-戈尔茨综合征：病例系列
Cureus. 2023 Sep 21;15(9):e45656. doi: 10.7759/cureus.45656. eCollection 2023 Sep.
7
Recurrence Patterns of Odontogenic Keratocysts in Syndromic and Non-Syndromic Patients.综合征型和非综合征型患者牙源性角化囊肿的复发模式
J Maxillofac Oral Surg. 2024 Feb;23(1):152-158. doi: 10.1007/s12663-023-01920-9. Epub 2023 Apr 24.
8
Changes in Cellular Regulatory Factors before and after Decompression of Odontogenic Keratocysts.牙源性角化囊肿减压前后细胞调节因子的变化
J Clin Med. 2020 Dec 24;10(1):30. doi: 10.3390/jcm10010030.
9
[Clinicopathological analysis of 844 cases of odontogenic keratocysts].844例牙源性角化囊肿的临床病理分析
Beijing Da Xue Xue Bao Yi Xue Ban. 2020 Feb 18;52(1):35-42. doi: 10.19723/j.issn.1671-167X.2020.01.006.
10
Surgical treatment of odontogenic keratocyst by enucleation.通过摘除术治疗牙源性角化囊肿。
Contemp Clin Dent. 2010 Oct;1(4):263-7. doi: 10.4103/0976-237X.76398.

引用本文的文献

1
Peripheral Odontogenic Keratocyst Presenting as a Gingival Nodular Mass in the Anterior Mandible: A Case Report.以下颌前部牙龈结节状肿物为表现的外周性牙源性角化囊肿：一例报告
Cureus. 2025 Feb 20;17(2):e79382. doi: 10.7759/cureus.79382. eCollection 2025 Feb.
2
Two-Dimensional Change in the Cystic Defects after Decompression and Enucleation of Jaw Cysts - A Comparative Study.颌骨囊肿减压与摘除术后囊性缺损的二维变化——一项对比研究
Ann Maxillofac Surg. 2021 Jul-Dec;11(2):241-246. doi: 10.4103/ams.ams_122_21. Epub 2022 Feb 1.
3
Decompression induces inflammation but do not modify cell proliferation and apoptosis in odontogenic keratocyst.

本文引用的文献

1
Controversies in Odontogenic Tumours: Review.牙源性肿瘤的争议：综述
Sultan Qaboos Univ Med J. 2017 Aug;17(3):e268-e276. doi: 10.18295/squmj.2017.17.03.003. Epub 2017 Oct 10.
2
The World Health Organization Classification of Odontogenic Lesions: A Summary of the Changes of the 2017 (4th) Edition.世界卫生组织牙源性病变分类：2017年（第4版）变化总结
Turk Patoloji Derg. 2018;34(1). doi: 10.5146/tjpath.2017.01410.
3
New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours.
减压会引发炎症，但不会改变牙源性角化囊肿中的细胞增殖和凋亡。
J Clin Exp Dent. 2022 Jan 1;14(1):e100-e106. doi: 10.4317/jced.59096. eCollection 2022 Jan.
4
Eruption of the Permanent First Premolar Associated with a Mandibular Keratocystic Odontogenic Tumor after Marsupialization in a 9-year-old Boy: A Case Report with 2 years of follow-up.一名9岁男孩袋形术治疗后，下颌角化囊性牙源性肿瘤伴恒牙第一前磨牙萌出：一项随访2年的病例报告
J Dent (Shiraz). 2021 Jun;22(2):144-148. doi: 10.30476/DENTJODS.2020.85780.1152.
5
Sub-epithelial hyalinization, incomplete cystic lining, and corrugated surface could be a predictor of recurrence in Odontogenic Keratocysts.上皮下玻璃样变、囊壁内衬不全及表面呈波纹状可能是牙源性角化囊肿复发的一个预测指标。
J Oral Biol Craniofac Res. 2021 Jul-Sep;11(3):423-429. doi: 10.1016/j.jobcr.2021.05.003. Epub 2021 May 12.
6
Immunohistochemical Characterization of Reactive Epithelial Changes in Odontogenic Keratocysts.牙源性角化囊肿中反应性上皮改变的免疫组织化学特征。
Pathol Oncol Res. 2020 Jul;26(3):1717-1724. doi: 10.1007/s12253-019-00749-3. Epub 2019 Oct 18.
7
The Changing Landscape in Treatment of Cystic Lesions of the Jaws.颌骨囊性病变治疗领域的变化态势
J Int Soc Prev Community Dent. 2019 Aug 6;9(4):328-337. doi: 10.4103/jispcd.JISPCD_180_19. eCollection 2019 Jul-Aug.
世界卫生组织头颈部肿瘤分类第4版中的新肿瘤实体：牙源性和颌面骨肿瘤。
Virchows Arch. 2018 Mar;472(3):331-339. doi: 10.1007/s00428-017-2182-3. Epub 2017 Jul 3.
4
Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors.世界卫生组织头颈部肿瘤分类第4版更新：牙源性和颌面骨肿瘤
Head Neck Pathol. 2017 Mar;11(1):68-77. doi: 10.1007/s12105-017-0794-1. Epub 2017 Feb 28.
5
Decompression as a treatment of odontogenic cystic lesions in children.减压术作为儿童牙源性囊性病变的一种治疗方法。
J Oral Maxillofac Surg. 2015 Apr;73(4):649-54. doi: 10.1016/j.joms.2014.10.024. Epub 2014 Oct 31.
6
Marsupialization is the optimal treatment approach for keratocystic odontogenic tumour.袋形术是治疗牙源性角化囊性瘤的最佳方法。
J Craniomaxillofac Surg. 2014 Oct;42(7):1540-4. doi: 10.1016/j.jcms.2014.04.027. Epub 2014 May 2.
7
Importance of Different Modalities of Treatment For the Management of Keratocystic Odontogenic Tumour with Five year follow-up.不同治疗方式对牙源性角化囊性瘤管理的重要性及五年随访
J Clin Diagn Res. 2014 Mar;8(3):225-8. doi: 10.7860/JCDR/2014/7486.4168. Epub 2014 Mar 15.
8
Morphometric evaluation of keratocystic odontogenic tumor before and after marsupialization.牙囊型角化囊性瘤去袋术后的形态计量学评价。
Braz Oral Res. 2013 Nov-Dec;27(6):496-502. doi: 10.1590/S1806-83242013000600009.
9
Odontogenic keratocyst: What is in the name?牙源性角化囊肿：名称中有何含义？
J Nat Sci Biol Med. 2013 Jul;4(2):282-5. doi: 10.4103/0976-9668.116968.
10
Kerathocyst Odontogenic Tumor: Importance of Selection the Best Treatment Modality and A Periodical Follow-up to Prevent from Recurrence: A Case Report and Literature Review.牙源性角化囊性瘤：选择最佳治疗方式及定期随访以预防复发的重要性：一例病例报告及文献综述
Int J Prev Med. 2013 Aug;4(8):967-70.