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牙源性角化囊肿治疗中减压后摘除术的临床及组织形态计量学评估

Clinical and histomorphometric evaluation of decompression followed by enucleation in the treatment of odontogenic keratocyst.

作者信息

Oh Ji-Su, You Jae-Seek, Kim Su-Gwan

机构信息

Department of Oral and Maxillofacial Surgery, School of Dentistry, Chosun University, Gwangju, Republic of Korea.

出版信息

J Dent Sci. 2018 Dec;13(4):329-333. doi: 10.1016/j.jds.2018.06.001. Epub 2018 Jun 18.

Abstract

BACKGROUND/PURPOSE: The classification and treatment of odontogenic keratocyst (OKC) are controversial. The objective of this study was to present the efficiency of decompression followed by enucleation by clinical and histomorphometric evaluation for the treatment of OKC.

MATERIALS AND METHODS

Thirty four OKCs of 27 patients who underwent decompression followed by enucleation were included in this study. Clinical and histomorphometric analysis were performed.

RESULTS

The average decreasing rate was 59% in maximum diameter, 66% in the amount of the volume for the average of period of the decompression was 9.8 months. The mean of increasing rate of the thickness of the epithelial lining was 921.16%. There were no recurrences for a mean follow-up period of 5.8 years. The thin and friable cyst wall of the OKC was changed to thickened, hard type.

CONCLUSION

The decompression was found to be effective and reliable as a treatment of the OKC to decrease the recurrence tendency, even for Gorlin-Goltz syndrome.

摘要

背景/目的:牙源性角化囊肿(OKC)的分类和治疗存在争议。本研究的目的是通过临床和组织形态计量学评估,呈现减压后摘除术治疗OKC的疗效。

材料与方法

本研究纳入了27例接受减压后摘除术的患者的34个OKC。进行了临床和组织形态计量学分析。

结果

减压平均时长为9.8个月,最大直径平均减小率为59%,体积平均减小率为66%。上皮衬里厚度的平均增加率为921.16%。平均随访5.8年无复发。OKC薄而脆的囊壁转变为增厚、坚硬型。

结论

减压作为一种治疗OKC的方法,被发现是有效且可靠的,可降低复发倾向,即使对于戈林-戈尔茨综合征患者也是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dbb/6388872/1bc613b54ea4/gr1.jpg

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