Centre for Endocrinology, Diabetes and Metabolism, Institute for Biomedical Research, School of Clinical and Experimental Medicine, University of Birmingham, UK.
Best Pract Res Clin Endocrinol Metab. 2011 Dec;25(6):975-83. doi: 10.1016/j.beem.2011.07.001.
Pregnancy and lactation are associated with profound changes in calcium physiology. This can make interpretation of biochemical tests difficult during these times. Diseases of bone and calcium metabolism are uncommon during pregnancy but can be severe when they occur. These conditions are complicated by the need for dual consideration for the maternal and foetal health. These conditions are also much less well studied than related conditions that occur outside of pregnancy resulting in a reduction in evidence for and confidence in recommendations relating to management. This chapter will review the changes in calcium physiology that occur with pregnancy and lactation, describe the disorders of calcium and parathyroid physiology that can occur and outline the most appropriate way to manage these conditions.
妊娠和哺乳期伴随着钙生理学的深刻变化。这可能使得在这些时期解读生化检验结果变得困难。妊娠期间骨骼和钙代谢疾病并不常见，但一旦发生可能很严重。这些情况使我们需要同时考虑母亲和胎儿的健康，变得更为复杂。这些疾病的研究也远不如非妊娠期间发生的相关疾病充分，导致管理相关建议的证据和信心减少。本章将回顾妊娠和哺乳期钙生理学的变化，描述可能发生的钙和甲状旁腺生理学紊乱，并概述处理这些疾病的最合适方法。
