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伯氏疏螺旋体中的青霉素结合蛋白

Penicillin-binding proteins in Borrelia burgdorferi.

作者信息

Urban C, Rahal J J, Dattwyller R J, Gorevic P, Luft B J

机构信息

Department of Medicine, Booth Memorial Medical Center, Flushing, New York 11355.

出版信息

J Bacteriol. 1990 Oct;172(10):6139-41. doi: 10.1128/jb.172.10.6139-6141.1990.

DOI:10.1128/jb.172.10.6139-6141.1990
PMID:2211530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC526942/
Abstract

Penicillin-binding proteins were identified in Borrelia burgdorferi membranes. A 94-kilodalton penicillin-binding protein was the first to be labeled with tritiated penicillin and was the first band to disappear in a competition experiment. Its binding ability was destroyed when membranes were preboiled. In addition, several of these penicillin-binding proteins comigrated with bands previously identified as surface proteins.

摘要

在伯氏疏螺旋体膜中鉴定出了青霉素结合蛋白。一种94千道尔顿的青霉素结合蛋白首先用氚标记的青霉素进行标记，并且在竞争实验中是第一个消失的条带。当膜预先煮沸时，其结合能力被破坏。此外，这些青霉素结合蛋白中的几种与先前鉴定为表面蛋白的条带迁移率相同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e8/526942/24e8e849c595/jbacter00164-0632-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e8/526942/b20b0900daab/jbacter00164-0631-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e8/526942/24e8e849c595/jbacter00164-0632-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e8/526942/b20b0900daab/jbacter00164-0631-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9e8/526942/24e8e849c595/jbacter00164-0632-a.jpg

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Identification of Treponema pallidum penicillin-binding proteins.梅毒螺旋体青霉素结合蛋白的鉴定
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