梅毒螺旋体青霉素结合蛋白的鉴定
Identification of Treponema pallidum penicillin-binding proteins.
作者信息
Cunningham T M, Miller J N, Lovett M A
机构信息
Department of Microbiology and Immunology, School of Medicine, University of California, Los Angeles 90024.
出版信息
J Bacteriol. 1987 Nov;169(11):5298-300. doi: 10.1128/jb.169.11.5298-5300.1987.
Abstract
Penicillin-binding proteins of 180, 89, 80, 68, 61, 41, and 38 kilodaltons were identified in Treponema pallidum (Nichols) by their covalent binding of [35S]benzylpenicillin. Penicillin-binding proteins are localized in the plasma membranes of many bacterial species and may serve as useful markers for determining plasma membrane intactness in T. pallidum fractionation studies.
摘要
通过[35S]苄青霉素的共价结合，在梅毒螺旋体（Nichols株）中鉴定出了分子量分别为180、89、80、68、61、41和38千道尔顿的青霉素结合蛋白。青霉素结合蛋白定位于许多细菌物种的质膜中，在梅毒螺旋体分级分离研究中，可作为确定质膜完整性的有用标记。
Zotero 插件