Immunization Services Division, Centers for Disease Control and Prevention, 1600 Clifton Road, MS A-19, Atlanta, GA 30333, United States.
Vaccine. 2012 Jan 11;30(3):503-5. doi: 10.1016/j.vaccine.2011.11.042. Epub 2011 Nov 23.
Data from the 2008 and 2009 National Immunization Survey-Teen were analyzed to determine age at initiation of the human papillomavirus vaccine (HPV) series among females 13-17 years (n=7594) and assess compliance with the recommended HPV dosing intervals. Among females who initiated the HPV series, 56.7% of females<13 years at the time of the HPV vaccine recommendation publication did so by age 13; while the majority of females 13-14 and 15-17 years at the time of the recommendation publication did so at ages 14 (44.4%) and 16 (46.7%), respectively. Forty-six percent of females who received three doses completed the vaccination series in a period longer than the recommended time interval. Series completion at an earlier age to ensure protection before sexual debut is optimal. Improved provider communication of the need for three doses for long-term protection and implementing clinical practice guidelines to use reminder-recall systems may increase HPV completion.
对 2008 年和 2009 年全国青少年免疫调查的数据进行了分析,以确定 13-17 岁女性(n=7594)开始人乳头瘤病毒(HPV)疫苗系列的年龄,并评估其是否符合推荐的 HPV 接种间隔。在开始 HPV 系列接种的女性中,在 HPV 疫苗推荐发布时年龄<13 岁的女性中,有 56.7%在 13 岁时接种;而在推荐发布时年龄为 13-14 岁和 15-17 岁的大多数女性,则分别在 14 岁(44.4%)和 16 岁(46.7%)时接种。46%接受三剂疫苗接种的女性在推荐的时间间隔内完成了疫苗接种系列。为了在初次性行为前确保保护,提前完成接种系列是最佳的。提高提供者对三剂疫苗接种以获得长期保护的必要性的沟通,并实施临床实践指南以使用提醒-召回系统,可能会增加 HPV 疫苗的接种率。