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精神疾病成人患者的吞咽困难:系统综述

Dysphagia is a common and serious problem for adults with mental illness: a systematic review.

机构信息

Department of Speech Pathology, Eastern Health, Peter James Centre, Mahoney's Road, Burwood East, Melbourne, VIC, Australia.

出版信息

Dysphagia. 2012 Mar;27(1):124-37. doi: 10.1007/s00455-011-9378-5. Epub 2011 Nov 26.

Abstract

Adults with mental illness may experience a higher incidence of dysphagia and choking due to factors such as medication side effects and behavioural abnormalities. The aim of this study was to determine the frequency of dysphagia and the most effective interventions for this population. Studies published up to August 2010 were sought via a comprehensive electronic database search (CINAHL, PsycINFO, MEDLINE, PubMed, Cochrane, and Embase). Studies reporting dysphagia frequency or dysphagia intervention outcomes in adults with mental illness were included. Two reviewers independently assessed study eligibility and quality, and the results were synthesised descriptively. Ten studies were identified, each describing dysphagia frequency or death due to choking asphyxiation. No studies evaluating intervention effectiveness were identified. Study quality was limited by subjective assessment of outcomes. Six studies presented dysphagia frequencies ranging from 9 to 42% in varying subgroups. Four studies presented the frequency of choking asphyxiation death, including a large survey that concluded that adults with organic mental illness were 43 times more likely to die of this cause than the general population. Dysphagia is a common and significant cause of morbidity and mortality in adults with mental illness and our review found that there is a lack of studies evaluating the effectiveness of intervention techniques.

摘要

患有精神疾病的成年人可能由于药物副作用和行为异常等因素而出现更高的吞咽困难和窒息发生率。本研究旨在确定该人群吞咽困难的频率和最有效的干预措施。通过全面的电子数据库搜索(CINAHL、PsycINFO、MEDLINE、PubMed、Cochrane 和 Embase),寻找截至 2010 年 8 月发表的研究。纳入了报告精神疾病成年人吞咽困难频率或吞咽困难干预结果的研究。两位审稿人独立评估研究的合格性和质量,并对结果进行描述性综合分析。确定了 10 项研究,每项研究都描述了吞咽困难频率或因窒息性窒息而死亡的情况。没有评估干预效果的研究。研究质量受到结果主观评估的限制。有 6 项研究报告了不同亚组中 9%至 42%的吞咽困难频率。有 4 项研究报告了窒息性窒息死亡的频率,包括一项大型调查,该调查得出的结论是,患有器质性精神疾病的成年人死于这种原因的可能性是普通人群的 43 倍。吞咽困难是精神疾病成年人发病率和死亡率的常见且重大原因,我们的综述发现,缺乏评估干预技术效果的研究。

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