肥厚型心肌病与超长耐力跑——两种互不相容的运动？

St George's University of London, Division of Cardiac & Vascular Sciences, London, UK.

J Cardiovasc Magn Reson. 2011 Nov 29;13(1):77. doi: 10.1186/1532-429X-13-77.

Regular and prolonged exercise is associated with increased left ventricular wall thickness that can overlap with hypertrophic cardiomyopathy (HCM). Differentiating physiological from pathological hypertrophy has important implications, since HCM is the commonest cause of exercise-related sudden cardiac death in young individuals. Most deaths have been reported in intermittent 'start-stop' sports such as football (soccer) and basketball. The theory is that individuals with HCM are unable to augment stroke volume sufficiently to meet the demands of endurance sports and are accordingly 'selected-out' of participation in such events. We report the case of an ultra-endurance athlete with 25 years of > 50 km competitive running experience, with genetically confirmed HCM; thereby demonstrating that these can be two compatible entities.

定期且长期的运动与左心室壁增厚有关，而这种增厚可能与肥厚型心肌病（HCM）相重叠。区分生理性和病理性肥大具有重要意义，因为 HCM 是年轻人运动相关心源性猝死的最常见原因。大多数死亡报告发生在间歇性“开始-停止”运动中，如足球（soccer）和篮球。理论是，患有 HCM 的个体无法充分增加每搏输出量以满足耐力运动的需求，因此被“淘汰”出此类运动。我们报告了一例超耐力运动员的病例，该运动员有 25 年的 > 50 公里竞赛跑步经验，且经基因证实患有 HCM；从而证明这两者可以并存。