New York Hospital Queens, Flushing, NY, USA.
J Addict Med. 2012 Mar;6(1):89-91. doi: 10.1097/ADM.0b013e3182399216.
Ketamine is a popular drug of abuse in China, especially for young adults between the 18 and 30 years. It produces desirable short-term sensations of excitement, dream-like states, hallucinations, and vivid imagery, but is also responsible for untoward effects of the gastrointestinal and urinary tracts. Abusers often present with severe abdominal pain and dysuria. In addition to its excretion in urine, ketamine is also excreted in bile and can lead to biliary dilatation. Sixteen reports of this phenomenon have been described in the literature, mostly in China. To date, this phenomenon has not been described in the United States. We present 2 cases of ketamine-induced biliary dilatation in young adult Asian patients. It is a new entity in the United States but should be recognized early, as it may prevent unnecessary investigation with blood work, imaging, therapeutic endoscopy, or even surgery.
氯胺酮在中国是一种流行的滥用药物，尤其在 18 至 30 岁的年轻人中。它会产生令人愉悦的短期兴奋感、梦幻状态、幻觉和生动的意象，但也会对胃肠道和泌尿道产生不良影响。滥用者常出现严重腹痛和尿痛。除了在尿液中排泄外，氯胺酮也会在胆汁中排泄，导致胆道扩张。文献中已经描述了 16 例这种现象，主要在中国。迄今为止，这种现象在美国尚未被描述。我们报告了 2 例年轻亚裔患者因氯胺酮引起的胆道扩张。在美国，这是一种新的病症，但应及早认识到这一点，因为它可以避免不必要的检查，如血液检查、影像学检查、治疗性内镜检查，甚至手术。
