Chang Guohao, Chan Ching Wan, Hartman Mikael
Department of Surgery, National University Hospital, and Department of Epidemiology and Public Health, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
Asian Pac J Cancer Prev. 2011;12(6):1635-9.
Breast cancer is the most common cancer in Singaporean women and the rate of increase in incidence is one of the highest in the world. In view of the significant contribution of delayed presentation to the disease burden in South East Asia, we reviewed the incidence of late presentation of breast cancer and the contributing factors in Singapore. Disease presentation was analysed using studies based on the Singapore Cancer Registry 2004-2008 and with data from women with breast cancer at the National University Hospital (NUH) in Singapore 1990-2007. Available literature from Singapore on factors contributing to delayed presentation was reviewed and presented here. The overall age-standardized 5-year relative survival for Singaporean women was 70% with only half diagnosed with localized cancer. Of all women diagnosed at NUH close to 20% presented at Stages III and IV. Given the magnitude of the problem of women presenting with more advanced stages of breast cancer, the National University of Singapore has joined a collaborative team with the University of Leeds (UK), the University of Malaya, and University of UAE to set up the UK-SEA-ME Psychosocial-Cultural Cancer Research Network to better understand late presentation.
乳腺癌是新加坡女性中最常见的癌症，其发病率的上升速度是世界上最快的之一。鉴于就诊延迟对东南亚疾病负担的重大影响，我们回顾了新加坡乳腺癌就诊延迟的发生率及相关影响因素。利用基于2004 - 2008年新加坡癌症登记处的研究以及1990 - 2007年新加坡国立大学医院（NUH）乳腺癌女性患者的数据对疾病就诊情况进行了分析。本文回顾并呈现了新加坡关于导致就诊延迟因素的现有文献。新加坡女性的总体年龄标准化5年相对生存率为70%，只有一半被诊断为局限性癌症。在NUH确诊的所有女性中，近20%在III期和IV期就诊。鉴于乳腺癌晚期就诊女性问题的严重性，新加坡国立大学已与英国利兹大学、马来亚大学和阿联酋大学组成一个合作团队，成立了英国 - 东南亚 - 中东社会心理 - 文化癌症研究网络，以更好地了解就诊延迟情况。
