Academic Medical Center, Department of Public Health, University of Amsterdam, Amsterdam, The Netherlands.
Lipids Health Dis. 2011 Nov 30;10:223. doi: 10.1186/1476-511X-10-223.
Evidence suggests that physical activity (PA) has a beneficial effect on high-density lipoprotein cholesterol (HDL) and triglycerides. However, observational studies show contrasting results for this association between different ethnic groups. It is unclear whether this is due to differences in the PA composition. The aim of this study was to assess the relationship of the total PA, along with its intensity and duration, with HDL and triglycerides in a multi-ethnic population.
The study population was sampled from the SUNSET study and included: 502 European- Dutch, 338 Hindustani-Surinamese, and 596 African-Surinamese participants living in Amsterdam, the Netherlands. We assessed PA with the SQUASH questionnaire. We calculated age-sex-adjusted betas, geometric mean ratios (GMRs), and prevalence ratios (PRs) to assess the relationship of PA with HDL and triglycerides.
In the adjusted models, the highest total PA tertile compared to the lowest tertile was beneficially associated with HDL (beta: 0.08, 95% CI: 0.00, 0.16 and PR low HDL 0.59, 95% CI: 0.39, 0.88) and triglycerides (GMR: 0.93, 95% CI: 0.83, 1.03 and PR: 0.56, 95% CI: 0.29, 1.08) for the African-Surinamese. No statistically significant associations appeared for total PA among the European-Dutch and Hindustani-Surinamese. The adjusted models with the intensity score and HDL showed beneficial associations for the European-Dutch (beta: 0.06, 95% CI: 0.03, 0.10) and African-Surinamese (beta: 0.06, 0.02, 0.10), for log triglycerides for the European-Dutch (beta: -0.08, 95% CI: -0.12, 0.03), Hindustani-Surinamese (beta: -0.06, 95% CI: -0.16, 0.03), and African-Surinamese (beta: -0.04, 95% CI: -0.10, 0.01). Excepting HDL in African-Surinamese, the duration score was unrelated to HDL and triglycerides in any group.
Activity intensity related beneficially to blood lipids in almost every ethnic group. The activity duration was unrelated to blood lipids, while the total PA 'summary score' was associated only with blood lipids for African-Surinamese. The difference in total PA composition is the most probable explanation for ethnic differences in the total PA association with blood lipids. Multi-ethnic observational studies should include not only a measure of the total PA, but other measures of PA as well, particularly the intensity of activity.
有证据表明，身体活动（PA）对高密度脂蛋白胆固醇（HDL）和甘油三酯有有益影响。然而，观察性研究显示，不同种族群体之间的这种关联结果存在差异。目前尚不清楚这是否是由于 PA 构成的差异所致。本研究旨在评估多民族人群中 PA 总量及其强度和持续时间与 HDL 和甘油三酯之间的关系。
研究人群来自 SUNSET 研究，包括 502 名荷兰裔欧洲人、338 名苏里南印度裔和 596 名苏里南非洲裔居住在荷兰阿姆斯特丹的参与者。我们使用 SQUASH 问卷评估 PA。我们计算了年龄性别调整后的β值、几何平均比（GMR）和患病率比（PR），以评估 PA 与 HDL 和甘油三酯的关系。
在调整模型中，与最低三分位相比，最高三分位的总 PA 与 HDL 呈正相关（β：0.08，95%CI：0.00，0.16 和 PR 低 HDL：0.59，95%CI：0.39，0.88）和甘油三酯（GMR：0.93，95%CI：0.83，1.03 和 PR：0.56，95%CI：0.29，1.08）与非洲裔苏里南人。荷兰裔欧洲人和印度裔苏里南人中，总 PA 与总 PA 之间没有统计学意义的关联。与 HDL 一起调整强度评分的模型显示，荷兰裔欧洲人（β：0.06，95%CI：0.03，0.10）和非洲裔苏里南人（β：0.06，0.02，0.10）具有有益的关联，荷兰裔欧洲人（β：-0.08，95%CI：-0.12，0.03）和印度裔苏里南人（β：-0.06，95%CI：-0.16，0.03）和非洲裔苏里南人（β：-0.04，95%CI：-0.10，0.01）的 log 甘油三酯。除了非洲裔苏里南人的 HDL 外，持续时间评分与任何组的 HDL 和甘油三酯均无关。
在几乎每个种族群体中，与血液脂质相关的活动强度都有益。活动持续时间与血液脂质无关，而总 PA“综合评分”仅与非洲裔苏里南人的血液脂质有关。总 PA 构成差异很可能是总 PA 与血液脂质关联的种族差异的最可能解释。多民族观察性研究不仅应包括对总 PA 的测量，还应包括对其他 PA 测量的测量，特别是活动的强度。
