Silva Raquel Caroline da, Diniz Maria de Fátima Haueisen Sander, Alvim Sheila, Vidigal Pedro Guatimosim, Fedeli Ligia Maria Giongo, Barreto Sandhi Maria
Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil.
Universidade Federal da Bahia, Salvador, BA, Brazil.
Arq Bras Cardiol. 2016 Jul;107(1):10-9. doi: 10.5935/abc.20160091. Epub 2016 Jun 23.
Regular physical activity (PA) induces desirable changes in plasma levels of high- and low-density lipoproteins (HDL and LDL, respectively) and triglycerides (TG), important risk factors for cardiometabolic diseases. However, doubts whether intensity and duration have equivalent benefits remain.
To assess the association of PA intensity and duration with HDL, LDL and TG levels.
Cross-sectional study with 12,688 participants from the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil) baseline, who were not on lipid-lowering medication. After adjustment for important covariates, multiple linear regression was used to assess the association of PA intensity and duration with HDL, LDL and TG (natural logarithm) levels.
Both moderate and vigorous PA and PA practice ≥ 150 min/week were significantly associated with higher HDL and lower TG levels. Vigorous PA was associated with lower LDL only on univariate analysis. After adjustments, moderate and vigorous PA increased mean HDL level by 0.89 mg/dL and 1.71 mg/dL, respectively, and reduced TG geometric mean by 0.98 mg/dL and 0.93 mg/dL, respectively. PA practice ≥ 150 min/week increased mean HDL level by 1.05 mg/dL, and decreased TG geometric mean by 0.98 mg/dL.
Our findings reinforce the benefits of both PA parameters studied on HDL and TG levels, with a slight advantage for vigorous PA as compared to the recommendation based only on PA duration.
规律的体育活动（PA）可使血浆中高密度脂蛋白和低密度脂蛋白（分别为HDL和LDL）以及甘油三酯（TG）水平发生有益变化，而这些是心脏代谢疾病的重要危险因素。然而，强度和持续时间是否具有同等益处仍存疑问。
评估PA强度和持续时间与HDL、LDL和TG水平之间的关联。
对巴西成人健康纵向研究（ELSA - Brasil）基线期的12688名未服用降脂药物的参与者进行横断面研究。在对重要协变量进行调整后，采用多元线性回归评估PA强度和持续时间与HDL、LDL和TG（自然对数）水平之间的关联。
中等强度和高强度PA以及每周PA锻炼≥150分钟均与较高的HDL水平和较低的TG水平显著相关。仅在单因素分析中，高强度PA与较低的LDL相关。调整后，中等强度和高强度PA分别使HDL平均水平升高0.89mg/dL和1.71mg/dL，使TG几何平均数分别降低0.98mg/dL和0.93mg/dL。每周PA锻炼≥150分钟使HDL平均水平升高1.05mg/dL，使TG几何平均数降低0.98mg/dL。
我们的研究结果强化了所研究的PA的两个参数对HDL和TG水平的益处，与仅基于PA持续时间的建议相比，高强度PA略有优势。
