Department of Physical Therapy, University of the Sciences, Philadelphia, PA 19104, USA.
Arch Phys Med Rehabil. 2011 Dec;92(12):1937-43. doi: 10.1016/j.apmr.2011.06.031.
To determine the effect of cycling, electrical stimulation, or both, on thigh muscle volume and stimulated muscle strength in children with spinal cord injury (SCI).
Randomized controlled trial.
Children's hospital specializing in pediatric SCI.
Children (N=30; ages, 5-13y) with chronic SCI.
Children were randomly assigned to 1 of 3 interventions: functional electrical stimulation cycling (FESC), passive cycling (PC), and noncycling, electrically stimulated exercise (ES). Each group exercised for 1 hour, 3 times per week for 6 months at home.
Preintervention and postintervention, children underwent magnetic resonance imaging to assess muscle volume, and electrically stimulated isometric muscle strength testing with the use of a computerized dynamometer. Data were analyzed via analyses of covariance (ANCOVA) with baseline measures as covariates. Within-group changes were assessed via paired t tests.
All 30 children completed the training. Muscle volume data were complete for 24 children (8 FESC, 8 PC, 8 ES) and stimulated strength data for 27 children (9 per group). Per ANCOVA, there were differences between groups (P<.05) for quadriceps muscle volume and stimulated strength, with the ES group having greater changes in volume and the FESC group having greater changes in strength. Within-group analyses showed increased quadriceps volume and strength for the FESC group and increased quadriceps volume for the ES group.
Children receiving either electrically stimulated exercise experienced changes in muscle size, stimulated strength, or both. These changes may decrease their risk of cardiovascular disease, insulin resistance, glucose intolerance, and type 2 diabetes.
NCT00245726.
确定骑单车、电刺激或两者结合对脊髓损伤（SCI）儿童大腿肌肉体积和受刺激肌肉力量的影响。
随机对照试验。
专门治疗儿科 SCI 的儿童医院。
患有慢性 SCI 的儿童（N=30；年龄，5-13 岁）。
儿童被随机分配到 3 种干预措施之一：功能性电刺激单车运动（FESC）、被动单车运动（PC）和非单车、电刺激运动（ES）。每个组在家中每天锻炼 1 小时，每周 3 次，共 6 个月。
干预前和干预后，儿童接受磁共振成像（MRI）评估肌肉体积，并使用计算机测力计进行受刺激等长肌肉力量测试。数据分析采用协方差分析（ANCOVA），以基线测量值作为协变量。通过配对 t 检验评估组内变化。
所有 30 名儿童均完成了训练。24 名儿童（8 名 FESC、8 名 PC、8 名 ES）完成了肌肉体积数据，27 名儿童（每组 9 名）完成了受刺激力量数据。根据 ANCOVA，组间存在差异（P<.05），ES 组肌肉体积和受刺激力量变化较大，FESC 组力量变化较大。组内分析显示 FESC 组股四头肌体积和力量增加，ES 组股四头肌体积增加。
接受电刺激运动的儿童的肌肉大小、受刺激力量或两者都发生了变化。这些变化可能降低他们患心血管疾病、胰岛素抵抗、葡萄糖耐量受损和 2 型糖尿病的风险。
NCT00245726。
