Spinal Cord Injury and Disorders Center, Hunter Holmes McGuire VAMC, 1201 Broad Rock Boulevard, Richmond, VA 23249, USA.
J Electromyogr Kinesiol. 2013 Aug;23(4):977-84. doi: 10.1016/j.jelekin.2013.04.007. Epub 2013 May 15.
The current study examined the effects of 12weeks of surface neuromuscular electrical stimulation (NMES) and ankle weights on the cross-sectional areas (CSAs) of three thigh [Gracilis (Gra), Sartorious (Sar) and Adductor (Add)] as well as two trunk [hip flexor (HF) and back extensor (BE)] muscle groups in men with spinal cord injury (SCI). Seven individuals with chronic motor complete SCI were randomly assigned into a resistance training +diet (RT+diet; n=4) or diet control (n=3) groups. The RT+diet group underwent twice weekly training with surface NMES and ankle weights for 12weeks. Training composed of four sets of 10 repetitions of leg extension exercise while sitting in their wheelchairs. Both groups were asked to monitor their dietary intake. Magnetic resonance images were captured before and after 12weeks of interventions. Gra muscle CSA showed no change before and after interventions. A significant interaction (P=0.001) was noted between both groups as result of 9% increase and 10% decrease in the Gra muscle CSA of the RT+diet and diet groups, respectively. Sar muscle CSA increased [1.7±0.4-2.5±0.5cm(2); P=0.029] in the RT+diet group with no change [2.9±1.4-2.6±1.3cm(2)] in the diet group; with interaction noted between both groups (P=0.002). Analysis of covariance indicated that Add muscle CSA was 38% greater in the RT+diet compared to the diet group (P=0.025) after 12weeks; a trend of interaction was also noted between both groups (P=0.06). HF and BE muscle groups showed no apparent changes in CSA in both groups. The results suggested that surface NMES can delay the process of progressive skeletal muscle atrophy after chronic SCI. However, the effects are localized to the trained thigh muscles and do not extend to the proximal trunk muscles.
本研究考察了 12 周表面神经肌肉电刺激（NMES）和脚踝重量对脊髓损伤（SCI）男性的三个大腿（内收肌（Gra）、缝匠肌（Sar）和内收肌（Add））以及两个躯干（髋关节屈肌（HF）和背伸肌（BE））肌肉群的横截面积（CSA）的影响。7 名慢性运动完全性 SCI 患者被随机分为阻力训练+饮食（RT+饮食；n=4）或饮食对照组（n=3）。RT+饮食组每周接受两次表面 NMES 和脚踝重量训练，共 12 周。训练由坐在轮椅上进行的 10 次腿部伸展运动的四组组成。两组均被要求监测饮食摄入。在干预前和 12 周后拍摄磁共振成像。干预前后 Gra 肌肉 CSA 无变化。RT+饮食组和饮食组的 Gra 肌肉 CSA 分别增加 9%和减少 10%，两组之间存在显著的相互作用（P=0.001）。RT+饮食组的 Sar 肌肉 CSA 增加[1.7±0.4-2.5±0.5cm(2); P=0.029]，饮食组无变化[2.9±1.4-2.6±1.3cm(2)]；两组之间存在相互作用（P=0.002）。协方差分析表明，与饮食组相比，RT+饮食组的 Add 肌肉 CSA 增加了 38%（P=0.025）；两组之间也存在相互作用的趋势（P=0.06）。HF 和 BE 肌肉群在两组中的 CSA 均无明显变化。结果表明，表面 NMES 可延缓慢性 SCI 后进行性骨骼肌萎缩的过程。然而，这些效果局限于受过训练的大腿肌肉，而不会扩展到近端躯干肌肉。
