氯吡格雷（波立维）。
Clopidogrel (plavix).
机构信息
Department of Radiology, St. Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia.
出版信息
AJNR Am J Neuroradiol. 2011 Dec;32(11):2002-4. doi: 10.3174/ajnr.A2913. Epub 2011 Dec 1.
Abstract
Clopidogrel is an inhibitor of platelet aggregation, indicated for the prevention of ischemic stroke and in-stent thrombosis. However, it has a number of drawbacks, including an increased risk of hemorrhage; a clinical effect that is slow in onset and irreversible; a genetically determined variability in its clinical potency; and interactions with other commonly administered drugs.
摘要
氯吡格雷是一种血小板聚集抑制剂，用于预防缺血性卒中和支架内血栓形成。然而，它有许多缺点，包括出血风险增加；临床效果起效慢且不可逆转；其临床疗效存在遗传决定的变异性；以及与其他常用药物的相互作用。
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本文引用的文献
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ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. A Report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents.美国心脏病学会基金会/美国胃肠病学会/美国心脏协会2010年质子泵抑制剂与噻吩并吡啶类药物联合使用专家共识文件：ACCF/ACG/AHA 2008年关于降低抗血小板治疗和非甾体抗炎药使用的胃肠道风险专家共识文件的重点更新。美国心脏病学会基金会专家共识文件特别工作组报告。
J Am Coll Cardiol. 2010 Dec 7;56(24):2051-66. doi: 10.1016/j.jacc.2010.09.010.
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Am J Gastroenterol. 2010 Jan;105(1):34-41. doi: 10.1038/ajg.2009.638. Epub 2009 Nov 10.
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Cost-effectiveness of clopidogrel plus aspirin versus aspirin alone for secondary prevention of cardiovascular events: results from the CHARISMA trial.氯吡格雷联合阿司匹林与单用阿司匹林在心血管事件二级预防中的成本效益：CHARISMA试验结果
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