Ouyang Ba-si, Gao Jie, Sun Gang, Pu Ming-zhi, Wu Yuan-jian, Fan Chun, Ji Ling-ling
Department of Acupuncture and Moxibustion, Suzhou Hospital of TCM, Suzhou 215003, Jiangsu Province, China.
Zhongguo Zhen Jiu. 2011 Nov;31(11):965-70.
To observe the impact of heat-sensitive moxibustion on lung function in chronic persistent bronchial asthma and analyze its effect on the improvement of life quality as well as compare its efficacy with Seretide inhaler.
Fifty-seven cases were divided into a heat-sensitive moxibustion group (28 cases) and a Seretide group (29 cases) according to the random number table. In heat-sensitive moxibustion group, the therapy of heat-sensitive moxibustion was applied to the regions at the level of Feishu (BL 13) and Geshu (BL 17), or to the heat-sensitized points in the region 6 cun lateral from the 1st and 2nd intercostal spaces in the chest. The treatment was given continuously for 8 days, once per day, 12 treatments should be ensured in the later 22 days of the 1st month. In the later two months since then, 15 treatments should be ensured each month (< or = 1 treatment each day). In Seretide group, Seritide manufactured in GlaxoSmithKLine was used, one inhalation each time, twice per day. The cases in both groups were received treatment for 3 months. The changes in lung function such as forced expiratory volume one second (FEV1), TCM symptoms score, Asthma Control Test (ACT) and St George's Respiratory Questionnaire (SGRQ) were assessed and compared between two groups and within group separately.
Lung function as FEV1 was improved in either group (P < 0.05, P < 0.01). The terminal improvement effects on symptoms of Chinese medicine, life quality and others were same between two groups (all P > 0.05). But the improvements in general situation, chills, fever and sweating in heat-sensitive moxibustion group were superior to those in Seretide group (both P < 0.05). Concerning to the improvement in respiratory symptoms, the effect of Seretide was better than that of heat-sensitive moxibustion (P < 0.05).
Heat-sensitive moxibustion improves lung function, relieves clinical symptoms and benefits life quality for patients with chronic persistent bronchial asthma. It's efficacy on the disease is equal to the internationally-recognized effect of Seretide.
观察热敏灸对慢性持续性支气管哮喘患者肺功能的影响，分析其对患者生活质量改善的作用，并与舒利迭吸入剂进行疗效对比。
将57例患者按随机数字表法分为热敏灸组（28例）和舒利迭组（29例）。热敏灸组采用热敏灸疗法，取双侧肺俞（BL 13）、膈俞（BL 17），或取胸部第1、2肋间，距前正中线旁开6寸区域内的热敏化腧穴进行治疗，连续治疗8天，每日1次，第1个月后22天保证治疗12次，此后2个月内每月保证治疗15次（每日≤1次）。舒利迭组使用葛兰素史克公司生产的舒利迭，每次吸入1吸，每日2次。两组均治疗3个月。分别比较两组组内及组间治疗前后第1秒用力呼气容积（FEV1）等肺功能指标、中医症状积分、哮喘控制测试（ACT）及圣乔治呼吸问卷（SGRQ）的变化。
两组治疗后FEV1等肺功能指标均较治疗前改善（P<0.05，P<0.01）。两组对中医症状、生活质量等方面的最终改善效果相当（均P>0.05）。但热敏灸组在总体状况、恶寒、发热、汗出等方面的改善优于舒利迭组（均P<0.05）。在改善呼吸症状方面，舒利迭的效果优于热敏灸（P<0.05）。
热敏灸可改善慢性持续性支气管哮喘患者的肺功能，缓解临床症状，提高生活质量，其对该病的疗效与国际公认的舒利迭相当。
