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[温阳益气针法对哮喘缓解期患者的影响及免疫功能研究]

[Impacts on asthma at persistent stage and immune function in the patients treated with acupuncture for warming yang and benefiting qi].

作者信息

Xie Yilin, Wan Wenrong, Zhao Yinlong, Xie Junjie, Wu Qiuyan

出版信息

Zhongguo Zhen Jiu. 2015 Nov;35(11):1089-93.

PMID:26939313
Abstract

OBJECTIVE

To compare the difference in clinical efficacy on bronchial asthma at chronic persistent stage between acupuncture for warming yang and benefiting qi and seretide.

METHODS

One hundred and eighty patients of bronchial asthma at chronic persistent stage were randomized into an acupuncture group and a western medication group, 90 cases in each one. In the acupuncture group, acupuncture for warming yang and benefiting qi was applied at Dazhui (GV 14), Feishu (BL 13), Danzhong (CV 17), Dingchuan (EX-B 1), Jianshi (PC 5), Zhigou (TE 6), Taixi (KI 3) and Zusanli (ST 36), once every two days. In the western medication group, inhalation therapy with seretide was applied, 1 to 2 inhalations each time, twice a day. The treatment for 20 days was as one session in the two groups, at the intervals of 2 days after each session. Four sessions of treatment were required. The immune function indices were observed before and after treatment in the patients of two groups, named immunoglobulin IgG, IgM and IgE; peripheral T lymphocytes (CD3+), helper T lymphocytes (CD4+), inhibitory T lymphocytes (CD8+) and the ratio of CD4+ and CD8+; as well as the pulmonary ventilation function indices, named maximum pulmonary expiratory flow (PEF), forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). The clinical efficacy was compared between the two groups.

RESULTS

The total effective rate was 93.3% (84/90) in the acupuncture group, better than 88.9% (80/90) in the western medication group (P < 0.05). After treatment, the immune function indices and pulmonary ventilation function indices were apparently improved as compared with those before treatment in the two groups (all P < 0.05). The improvements in the acupuncture group were much more significant (all P < 0.05).

CONCLUSION

Acupuncture for warming yang and benefiting qi effectively controls the symptoms of bronchial asthma at chronic persistent stage and improves immune and pulmonary functions. The efficacy is better than that of seretide.

摘要

目的

比较温阳益气针法与舒利迭治疗支气管哮喘慢性持续期的临床疗效差异。

方法

将180例支气管哮喘慢性持续期患者随机分为针刺组和西药组,每组90例。针刺组采用温阳益气针法针刺大椎(GV 14)、肺俞(BL 13)、膻中(CV 17)、定喘(EX - B 1)、间使(PC 5)、支沟(TE 6)、太溪(KI 3)、足三里(ST 36),每两日1次。西药组采用舒利迭吸入治疗,每次1~2吸,每日2次。两组均以20天治疗为1个疗程,疗程间间隔2天,共治疗4个疗程。观察两组患者治疗前后免疫功能指标,即免疫球蛋白IgG、IgM、IgE;外周血T淋巴细胞(CD3 +)、辅助性T淋巴细胞(CD4 +)、抑制性T淋巴细胞(CD8 +)及CD4 +/CD8 +比值;以及肺通气功能指标,即最大呼气流量(PEF)、第1秒用力呼气容积(FEV1)、用力肺活量(FVC)。比较两组临床疗效。

结果

针刺组总有效率为93.3%(84/90),优于西药组的88.9%(80/90)(P < 0.05)。治疗后,两组免疫功能指标和肺通气功能指标均较治疗前明显改善(均P < 0.05),针刺组改善更显著(均P < 0.05)。

结论

温阳益气针法能有效控制支气管哮喘慢性持续期症状,改善免疫及肺功能,疗效优于舒利迭。

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