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使用重组人骨形态发生蛋白-2(rhBMP-2)和钛网对萎缩性下颌后牙区进行骨增量以植入牙种植体:临床技术及早期结果

Bone augmentation of the atrophic posterior mandible for dental implants using rhBMP-2 and titanium mesh: clinical technique and early results.

作者信息

Misch Craig M

机构信息

New York, University College of Dentistry, New York, NY, USA.

出版信息

Int J Periodontics Restorative Dent. 2011 Nov-Dec;31(6):581-9.

PMID:22140660
Abstract

The atrophic posterior mandible has unique challenges when implant placement is planned. The purpose of this case series was to evaluate the use of recombinant human bone morphogenetic protein 2÷acelluar collagen sponge (rhBMP-2÷ACS) and titanium mesh for augmentation of the atrophic posterior mandible prior to implant insertion. The case series included five patients with inadequate bone in the posterior mandible for implant placement. The residual ridges were augmented with rhBMP-2÷ACS and a small amount of bone substitute. Titanium mesh was used to protect the graft sites. Dental implants were inserted after 6 months of healing. Healing of the grafted ridges was uneventful. Dental implants were placed in all grafted sites without the need for further bone augmentation. All 10 implants integrated well and were restored with single crowns. The use of rhBMP-2÷ACS with titanium mesh was effective in this case series for augmentation of the atrophic posterior mandible prior to implant placement. This approach offers many advantages, including technical ease, no need for bone harvesting, decreased morbidity, and reduced surgical time.

摘要

当计划进行种植体植入时,萎缩的下颌后部存在独特的挑战。本病例系列的目的是评估重组人骨形态发生蛋白2-无细胞胶原海绵(rhBMP-2-ACS)和钛网在种植体植入前用于萎缩下颌后部骨增量的效果。该病例系列包括5例下颌后部骨量不足无法进行种植体植入的患者。残余牙槽嵴用rhBMP-2-ACS和少量骨替代物进行增量。使用钛网保护植骨部位。愈合6个月后植入牙种植体。植骨后的牙槽嵴愈合顺利。所有移植部位均植入了牙种植体,无需进一步的骨增量。所有10枚种植体均良好整合,并采用单冠修复。在本病例系列中,rhBMP-2-ACS与钛网联合使用在种植体植入前用于萎缩下颌后部骨增量是有效的。这种方法具有许多优点,包括技术操作简便、无需取骨、发病率降低以及手术时间缩短。

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