Unité Mixte de Recherche Contrôle des Maladies Animales Exotiques et Emergentes (UMRCMAEE), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD), Sainte Clotilde, La Réunion, France.
Am J Trop Med Hyg. 2011 Dec;85(6):1097-9. doi: 10.4269/ajtmh.2011.11-0470.
In the last decade, leptospirosis has emerged as a globally important infectious disease. Humans most commonly become infected through occupational, recreational, or domestic contact with the urine of carrier animals, either directly or through contaminated water or soil. The disease occurs in urban areas of industrialized and developing countries as well as rural regions worldwide. We present a retrospective study conducted in 2006 on 2,269 randomly selected Reunion Island inhabitants. Blood sampling was performed on individual blotting papers, and microscopic agglutination test (MAT) was conducted on paper disc-absorbed (PDA) blood. We showed that seroprevalence of leptospirosis was 0.66% ± 0.34 in the global population of Reunion Island, which is 1.78 lower than the seroprevalence estimated 20 years before. The serological method is described, and the results discussion focuses on methodology and socio-economic factors.
在过去的十年中，钩端螺旋体病已成为一种具有全球重要意义的传染病。人类主要通过与携带动物的尿液直接接触或通过受污染的水或土壤间接接触职业、娱乐或家庭接触而感染。该疾病发生在工业化和发展中国家的城市地区以及全球的农村地区。我们介绍了 2006 年对随机选择的 2269 名留尼汪岛居民进行的回顾性研究。在个体吸墨纸上进行血液采样，并在纸片吸收（PDA）血液上进行显微镜凝集试验（MAT）。我们表明，留尼汪岛全球人群的钩端螺旋体病血清流行率为 0.66%±0.34，比 20 年前估计的血清流行率低 1.78。描述了血清学方法，结果讨论集中在方法学和社会经济因素上。
