Cortellini G, Spadolini I, Santucci A, Cova V, Conti C, Corvetta A, Passalacqua G
Rimini Hospital, Internal Medicine, Rimini, Italy.
Eur Ann Allergy Clin Immunol. 2011 Oct;43(5):162-4.
The appropriateness of house dust mite specific immunotherapy in patients allergic to shrimps still remains unclear We present a clinical case as an immunological model for the strong sensitization to tropomyosin with symptoms of anaphylaxis due to shrimps and coexisting asthma due to house dust mite. The improvement in respiratory symptoms for house dust mite and in the food challenge for shrimps during mite immunotherapy with a known and high dosage of tropomyosin suggests the hypothesis that efficacy of mite immunotherapy in food allergy to tropomyosin may be dose dependent.
对于对虾过敏的患者，屋尘螨特异性免疫疗法的适用性仍不明确。我们报告一例临床病例，作为对原肌球蛋白强烈致敏的免疫学模型，该患者因虾出现过敏反应症状，并因屋尘螨共存哮喘。在用已知高剂量原肌球蛋白进行螨免疫治疗期间，屋尘螨引起的呼吸道症状改善以及对虾的食物激发试验结果改善，提示了螨免疫疗法对原肌球蛋白食物过敏的疗效可能取决于剂量这一假说。
