Sarkisova K Iu
Zh Vyssh Nerv Deiat Im I P Pavlova. 2011 Sep-Oct;61(5):624-30.
Behavior of male and female WAG/Rij and Wistar rats was compared in the tests assessing the level of anxiety (light-dark choice, open field) and depression-like state (sucrose intake and preference, forced swimming). Females of WAG/Rij rats like males of the same strain exhibited symptoms of depression-like behavior: increased immobility in the forced swimming test and decreased sucrose intake and preference (anhedonia). In contrast to males, females of WAG/Rij rats displayed more distinct signs of increased anxiety as compared to Wistar rats. Both WAG/Rij and Wistar females exhibited increased locomotor and exploratory activity in the open field as compared to males.
在评估焦虑水平(明暗选择、旷场试验)和抑郁样状态(蔗糖摄入和偏好、强迫游泳)的测试中,对雄性和雌性WAG/Rij大鼠及Wistar大鼠的行为进行了比较。与同品系雄性大鼠一样,WAG/Rij大鼠的雌性也表现出抑郁样行为症状:在强迫游泳试验中不动时间增加,蔗糖摄入量和偏好降低(快感缺失)。与雄性不同,与Wistar大鼠相比,WAG/Rij大鼠的雌性表现出更明显的焦虑增加迹象。与雄性相比,WAG/Rij和Wistar雌性大鼠在旷场试验中均表现出运动和探索活动增加。