Alamneh Tazebew Tilahun, Tilahun Shitahun Fente, Beyne Melkamu Bedimo, Fekadu Sofonias Addis, Assem Abel Sinshaw, Kassa Selam Fisiha
Department of Pediatrics and Child Health, School of Medicine, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.
Department of Pediatrics and Child Health, School of Medicine, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia.
Int J Gen Med. 2022 Aug 6;15:6465-6474. doi: 10.2147/IJGM.S365817. eCollection 2022.
Anemia is a common hematological problem in neonatal admissions. Poor detection rate and inappropriate treatment adversely affect the growing infant. Data on the magnitude and risk factors of anemia in sick newborns are lacking in Ethiopia, so knowing the prevalence and risk factors may reduce the long-term untreated complications of anemia.
The overall aim of this study was to assess the prevalence and associated factors of anemia among newborns admitted to Tibebe Ghion specialized hospital.
A hospital-based cross-sectional study was conducted among 272 newborns admitted to Tibebe Ghion Specialized Hospital from February 1 to May 30, 2021. A pretested structured questionnaire containing socio-demographic, clinical, and laboratory parameters was used for the data collection. Data were collected by trained nurses and residents after obtaining ethical clearance. The data were entered through Epi-data version 4.6 and analyzed using SPSS version 23.0 computer software. Descriptive statistics were performed using frequency, mean and standard deviation. Bivariable and multivariable binary logistic regressions were done to identify risk factors of anemia. Adjusted odds ratio with 95% confidence interval at a p-value <0.05 was declared as a statistically significant variable in the multivariable logistic regression.
About two-thirds 177 (65.1%) of the newborn babies were male and 152 (55.9%) of the newborn had a birth weight of ≥2500 grams. The most commonly diagnosed medical conditions were sepsis 218 (80.1%) and prematurity of birth 78 (28.7%). The prevalence of anemia among newborns in this study was 63 (23.2%) [19.1-28.7%]. Gestational age of 33-36 weeks (AOR=0.36: 95% CI=0.17-0.96) and maternal anemia (AOR=3.81: 95% CI=1.29-11.23) were significantly associated with newborn anemia.
The prevalence of anemia among newborns in Tibebe Ghion specialized hospital was high. Gestational age and maternal anemia were significantly associated with newborn anemia. So, it is better to properly educate and advise women about newborn anemia during antenatal care follow-up.
贫血是新生儿住院期间常见的血液学问题。低检出率和不恰当的治疗会对成长中的婴儿产生不利影响。埃塞俄比亚缺乏患病新生儿贫血的严重程度和危险因素的数据,因此了解患病率和危险因素可能会减少贫血长期未治疗的并发症。
本研究的总体目标是评估在提贝贝·吉翁专科医院住院的新生儿中贫血的患病率及相关因素。
于2021年2月1日至5月30日对提贝贝·吉翁专科医院收治的272例新生儿进行了一项基于医院的横断面研究。使用一份经过预测试的结构化问卷收集社会人口学、临床和实验室参数数据。在获得伦理批准后,由经过培训的护士和住院医师收集数据。数据通过Epi-data 4.6版本录入,并使用SPSS 23.0计算机软件进行分析。使用频率、均值和标准差进行描述性统计。进行双变量和多变量二元逻辑回归以确定贫血的危险因素。在多变量逻辑回归中,p值<0.05且95%置信区间的调整比值比被视为具有统计学意义的变量。
约三分之二(177例,65.1%)的新生儿为男性,152例(55.9%)新生儿出生体重≥2500克。最常诊断的疾病是败血症(218例,80.1%)和早产(78例,28.7%)。本研究中新生儿贫血的患病率为63例(23.2%)[19.1 - 28.7%]。孕龄33 - 36周(调整比值比=0.36:95%置信区间=0.17 - 0.96)和母亲贫血(调整比值比=3.81:95%置信区间=1.29 - 11.23)与新生儿贫血显著相关。
提贝贝·吉翁专科医院新生儿贫血的患病率较高。孕龄和母亲贫血与新生儿贫血显著相关。因此,在产前检查随访期间,最好对女性进行关于新生儿贫血的适当教育和建议。