Jung Hee-Dam, Kim Hei-Sung, Park Young-Min, Kim Hyung-Ok, Lee Jun-Young
Department of Dermatology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ann Dermatol. 2011 Oct;23(Suppl 2):S270-3. doi: 10.5021/ad.2011.23.S2.S270. Epub 2011 Oct 31.
Granulocytic sarcoma is an extramedullary tumor composed of granulocytic precursor cells. It usually presents as a nodular mass in the course of acute myelogenous leukemia. Rarely, the tumor develops in non-hematological conditions or in a patient with complete remission from the acute myelogenous leukemia. In such cases, aleukemic granulocytic sarcoma can be a preceding sign of systemic leukemia or a first sign of hematologic relapse of leukemia. We present an unusual case of multiple granulocytic sarcomas developed in a patient with longstanding complete remission of acute myelogenous leukemia, who has not had bone marrow and peripheral blood involvement for a long time.
粒细胞肉瘤是一种由粒细胞前体细胞组成的髓外肿瘤。它通常在急性髓系白血病病程中表现为结节状肿块。很少见的是，该肿瘤在非血液系统疾病或急性髓系白血病完全缓解的患者中发生。在这种情况下，无白血病粒细胞肉瘤可能是全身性白血病的前驱征象或白血病血液学复发的首发征象。我们报告一例罕见病例，一名急性髓系白血病长期完全缓解、长期无骨髓和外周血受累的患者发生了多发性粒细胞肉瘤。
