Suppr超能文献

二氢沉香呋喃衍生物从雷公藤的干燥根。

Dihydroagarofuran derivatives from the dried roots of Tripterygium wilfordii.

机构信息

Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, People's Republic of China.

出版信息

J Nat Prod. 2012 Jan 27;75(1):98-102. doi: 10.1021/np200493t. Epub 2011 Dec 12.

Abstract

Five new sesquiterpene derivatives, including dihydroagarofuran pyridine macrolides 1-4 and dihydroagarofuran ester 18, and 13 known dihydroagarofuran derivatives were isolated from the aqueous EtOH extract of the dried roots of Tripterygium wilfordii. An in vitro antiherpetic activity assay indicated that compounds 11 and 17 displayed weak and moderate inhibition against herpes simplex virus type II, respectively.

摘要

从雷公藤干燥根的水乙醇提取物中分离得到了五个新的倍半萜类衍生物,包括二氢沉香呋喃吡啶大环内酯 1-4 和二氢沉香呋喃酯 18,以及 13 个已知的二氢沉香呋喃衍生物。体外抗疱疹病毒活性测定表明,化合物 11 和 17 分别对单纯疱疹病毒 II 型具有弱抑制和中等抑制作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验