天然含氮倍半萜及其生物活性：综述。
Natural Nitrogenous Sesquiterpenoids and Their Bioactivity: A Review.
机构信息
Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Medical College, No. 151, Malianwa North Road, Haidian District, Beijing 100193, China.
Hainan Branch of Institute of Medicinal Plant Development, Chinese Academy of Medicinal Sciences & Peking Union Medical College (Hainan Provincial Key Laboratory of Resources Conservation and Development of Southern Medicine), Haikou 570311, China.
出版信息
Molecules. 2020 May 27;25(11):2485. doi: 10.3390/molecules25112485.
Nitrogenous sesquiterpenoids fromnatural sourcesare rare, so unsurprisingly neither the potentially valuable bioactivity nor thebroad structural diversity of nitrogenous sesquiterpenoids has been reviewed before. This report covers the progressduring the decade from 2010 to February 2020 on the isolation, identification, and bioactivity of 391 nitrogen-containing natural sesquiterpenes from terrestrial plant, marine organisms, and microorganisms. This complete and in-depth reviewshouldbe helpful for discovering and developing new drugs of medicinal valuerelated to natural nitrogenous sesquiterpenoids.
天然来源的含氮倍半萜类化合物较为罕见，因此，含氮倍半萜类化合物具有潜在的有价值的生物活性和广泛的结构多样性，这一点之前并未得到过综述。本报告涵盖了 2010 年至 2020 年 2 月期间，从陆生植物、海洋生物和微生物中分离、鉴定和研究 391 种含氮天然倍半萜的进展。本综述涵盖全面且深入，有助于发现和开发与天然含氮倍半萜类化合物相关的具有药用价值的新药。
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