新型 RNA 修饰。
Novel modifications in RNA.
机构信息
Department of Chemistry, University of California, Davis, 95616, United States.
出版信息
ACS Chem Biol. 2012 Jan 20;7(1):100-9. doi: 10.1021/cb200422t. Epub 2011 Dec 23.
Abstract
The past several years have seen numerous reports of new chemical modifications for use in RNA. In addition, in that time period, we have seen the discovery of several previously unknown naturally occurring modifications that impart novel properties on the parent RNAs. In this review, we describe recent discoveries in these areas with a focus on RNA modifications that introduce spectroscopic tags, reactive handles, or new recognition properties.
摘要
过去几年中，有许多关于用于 RNA 的新化学修饰的报道。此外，在那段时间里，我们发现了几种以前未知的天然存在的修饰，这些修饰赋予了亲本 RNA 新的性质。在这篇综述中，我们描述了这些领域的最新发现，重点介绍了引入光谱标记、反应性接头或新识别特性的 RNA 修饰。
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