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脊髓刺激治疗慢性疼痛管理的长期疗效。

Long-term outcome of spinal cord stimulation for chronic pain management.

机构信息

Division of Functional Neurosurgery, Thomas Jefferson University, Philadelphia.

出版信息

Neuromodulation. 1998 Jan;1(1):19-29. doi: 10.1111/j.1525-1403.1998.tb00027.x.

Abstract

Study Design. This is a retrospective study on 102 patients subjected to implantation of a spinal cord stimulation system for nonmalignant chronic pain management. The study was conducted through an extensive questionnaire and telephone interviews by a neutral third party. All the patients were implanted with a complete spinal cord stimulation system without a preliminary trial with a temporarily implanted electrode. Diagnostic categories were neuropathic pain, failed back syndrome, spinal cord Injury pain, and miscellaneous. Average follow-up was 3.8 years (6 months to 8 years). Patients were divided in two groups: all the implanted patients in the survey (Group A) and the implanted patients who experienced some degree of pain relief with the stimulation (Group B). Group B (80 patients) closely matches previously published series where an initial temporary screening was performed. Results. Twenty-one percent of the patients never experienced any pain relief. Of the remaining 80, 75% were still using the stimulator. Fifty-one percent of the 80 patients were experiencing good to excellent results and 20% moderate results. There was no reduction over time in the amount of pain relief in patients who initially had at least 75% pain relief. Patients with initial pain relief between 50% and 74% observed a moderate reduction in their pain relief after two years. Patients who initially experienced less than 50% pain relief observed a dramatic reduction in their results in the long term follow-up. Psychological screening contributed to the success of the procedure. Conclusions. With proper medical and psychological screening and with demonstrated initial pain relief, spinal cord stimulation remains an effective modality in the long-term management of severe chronic pain.

摘要

研究设计。这是一项针对 102 名接受脊髓刺激系统植入术治疗非恶性慢性疼痛管理的患者的回顾性研究。该研究通过广泛的问卷和中立第三方的电话访谈进行。所有患者均植入完整的脊髓刺激系统,而未进行临时植入电极的初步试验。诊断类别为神经性疼痛、失败后综合征、脊髓损伤疼痛和其他。平均随访时间为 3.8 年(6 个月至 8 年)。患者分为两组:接受调查的所有植入患者(A 组)和植入后在刺激下经历一定程度疼痛缓解的患者(B 组)。B 组(80 例)与先前发表的系列研究结果非常匹配,其中进行了初步的临时筛选。结果。21%的患者从未经历过任何缓解疼痛。在其余的 80 例中,75%仍在使用刺激器。80 例患者中有 51%的患者获得良好至极好的结果,20%的患者获得中等结果。在最初至少有 75%疼痛缓解的患者中,疼痛缓解的程度随时间的推移没有减少。在最初疼痛缓解在 50%至 74%之间的患者中,两年后其疼痛缓解程度观察到中度降低。在最初疼痛缓解低于 50%的患者中,其长期随访结果显著降低。心理筛查有助于手术的成功。结论。通过适当的医学和心理筛查,并在最初显示出疼痛缓解,脊髓刺激仍然是长期管理严重慢性疼痛的有效方法。

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