Area of Medicine for Children and Teenagers, University of Brasilia, Brasilia, Brazil.
Physiol Meas. 2012 Jan;33(1):39-49. doi: 10.1088/0967-3334/33/1/39. Epub 2011 Dec 7.
The Premature Infant Pain Profile (PIPP) is a promising multidimensional tool for comparison and testing of new technologies in newborn pain assessment studies since it may adhere to basic psychophysical parameters of intensity, direction, reactivity, regulation and slope described in analyses of physiological pain indicators. The aim of this study was to evaluate whether these psychophysical parameters can be achieved using the PIPP in acute pain assessment. Thirty-six healthy term newborn infants were conveniently sampled whilst being videotaped before, during and after heel prick blood sampling. The images were blind-scored by three trained independent raters and scored against the PIPP. The PIPP and its facial action indicators met the parameters of intensity, reactivity and regulation (all p < 0.001). The heart rate variability did not meet any parameter (all p > 0.05). The oxygen saturation variability met only the intensity parameter (p < 0.05). The behavioural state indicator met all parameters and had the best correlation to the psychophysical parameters of all indicators of PIPP (all p < 0.001). We concluded that the overall PIPP meets the assumptions of these psychophysical parameters, being the behavioural state indicator which best fit the model.
早产儿疼痛概况量表（PIPP）是一种有前途的多维工具，可用于比较和测试新生儿疼痛评估研究中的新技术，因为它可能符合生理疼痛指标分析中描述的强度、方向、反应性、调节和斜率等基本心理物理参数。本研究旨在评估 PIPP 是否可用于急性疼痛评估中这些心理物理参数的评估。36 名健康的足月新生儿在足跟采血前、采血期间和采血后被方便地采集录像。对图像进行了三名训练有素的独立评分员的盲法评分，并与 PIPP 进行了评分。PIPP 及其面部动作指标符合强度、反应性和调节参数（均 p<0.001）。心率变异性不符合任何参数（均 p>0.05）。血氧饱和度变异性仅符合强度参数（p<0.05）。行为状态指标符合所有参数，与 PIPP 所有指标的心理物理参数相关性最好（均 p<0.001）。我们得出结论，整体 PIPP 符合这些心理物理参数的假设，行为状态指标最符合该模型。
