Merrrill Palmer Skillman Institute, Wayne State University, Detroit, MI 48202, USA.
Nicotine Tob Res. 2012 Mar;14(3):351-60. doi: 10.1093/ntr/ntr221. Epub 2011 Dec 9.
Implementation of evidence-based interventions for smoking during pregnancy is challenging. We developed 2 highly replicable interventions for smoking during pregnancy: (a) a computer-delivered 5As-based brief intervention (CD-5As) and (b) a computer-assisted, simplified, and low-intensity contingency management (CM-Lite).
A sample of 110 primarily Black pregnant women reporting smoking in the past week were recruited from prenatal care clinics and randomly assigned to CD-5As (n = 26), CM-Lite (n = 28), CD-5As plus CM-Lite (n = 30), or treatment as usual (n = 26). Self-report of smoking, urine cotinine, and breath CO were measured 10 weeks following randomization.
Participants rated both interventions highly (e.g., 87.5% of CD-5As participants reported increases in likelihood of quitting), but most CM-Lite participants did not initiate reinforcement sessions and did not show increased abstinence. CD-5As led to increased abstinence as measured by cotinine (43.5% cotinine negative vs. 17.4%; odds ratio [OR] = 10.1, p = .02) but not for CO-confirmed 7-day point prevalence (30.4% abstinent vs. 8.7%; OR = 5.7, p = .06). Collapsing across CM-Lite status, participants receiving the CD-5As intervention were more likely to talk to a doctor or nurse about their smoking (60.5% vs. 30.8%; OR = 3.0, p = .02).
Low-intensity participant-initiated CM did not affect smoking in this sample, but the CD-5As intervention was successful in increasing abstinence during pregnancy. Further research should seek to replicate these results in larger and more diverse samples. Should CD-5As continue to prove efficacious, it could greatly increase the proportion of pregnant smokers who receive an evidence-based brief intervention.
实施基于证据的孕妇吸烟干预措施具有挑战性。我们开发了 2 种高度可复制的孕妇吸烟干预措施:(a)基于计算机的 5A 法简短干预(CD-5As)和(b)计算机辅助、简化和低强度的条件管理(CM-Lite)。
从产前保健诊所招募了 110 名主要为黑人的孕妇,这些孕妇报告在过去一周内吸烟,他们被随机分配到 CD-5As(n = 26)、CM-Lite(n = 28)、CD-5As 加 CM-Lite(n = 30)或常规治疗(n = 26)组。在随机分组后 10 周测量自我报告的吸烟情况、尿液可替宁和呼气 CO。
参与者对这两种干预措施的评价都很高(例如,87.5%的 CD-5As 参与者表示戒烟的可能性增加),但大多数 CM-Lite 参与者没有开始强化治疗,也没有表现出更高的戒烟率。CD-5As 导致可替宁检测的戒烟率增加(43.5%可替宁阴性与 17.4%;比值比[OR] = 10.1,p =.02),但呼气 CO 检测的 7 天点患病率没有增加(30.4%与 8.7%;OR = 5.7,p =.06)。综合考虑 CM-Lite 的状态,接受 CD-5As 干预的参与者更有可能与医生或护士谈论他们的吸烟问题(60.5%与 30.8%;OR = 3.0,p =.02)。
在这个样本中,低强度的参与者发起的 CM 对吸烟没有影响,但 CD-5As 干预成功地增加了怀孕期间的戒烟率。进一步的研究应该在更大和更多样化的样本中复制这些结果。如果 CD-5As 继续证明有效,它将大大增加接受基于证据的简短干预的孕妇吸烟者的比例。