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Highly sensitive MRD tests for ALL based on the IKZF1 Δ3-6 microdeletion.

作者信息

Venn N C, van der Velden V H J, de Bie M, Waanders E, Giles J E, Law T, Kuiper R P, de Haas V, Mullighan C G, Haber M, Marshall G M, Md Norris, van Dongen J J M, Sutton R

出版信息

Leukemia. 2012 Jun;26(6):1414-6. doi: 10.1038/leu.2011.348. Epub 2011 Dec 9.

DOI:10.1038/leu.2011.348
PMID:22157735
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3377997/
Abstract
摘要

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Leukemia. 2011 Feb;25(2):254-8. doi: 10.1038/leu.2010.275. Epub 2010 Nov 19.
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IKZF1 deletions predict relapse in uniformly treated pediatric precursor B-ALL.IKZF1 缺失可预测经统一治疗的儿童前体 B-ALL 的复发。
Leukemia. 2010 Jul;24(7):1258-64. doi: 10.1038/leu.2010.87. Epub 2010 May 6.
3
Standardized MRD quantification in European ALL trials: proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18-20 September 2008.
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Whole-genome sequencing facilitates patient-specific quantitative PCR-based minimal residual disease monitoring in acute lymphoblastic leukaemia, neuroblastoma and Ewing sarcoma.全基因组测序有助于急性淋巴细胞白血病、神经母细胞瘤和尤文肉瘤患者特异性基于定量 PCR 的微小残留病监测。
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