Thai A C, Kek L P, Ng W Y, Viegas O A, Rauff M
Department of Medicine, National University Hospital, Singapore.
Ann Acad Med Singap. 1990 Jul;19(4):477-9.
Serum fructosamine levels in women at pregnancy (28 weeks' gestation) were determined. The women (n = 99) also participated in an oral glucose tolerance test (OGTT) with a 75g liquid glucose load, to determine their glucose tolerance. At 32 weeks' gestation, seventy-nine of them repeated the oral glucose tolerance test and fructosamine measurement. Results showed that fructosamine levels in pregnant women with normal glucose tolerance (2.20 +/- 0.19 mmol/l, n = 76), were not statistically different from those with glucose intolerance (gestational diabetes: 2.19 +/- 0.22 mmol/l, n = 23) at 28 weeks' and also 32 weeks' gestation. However, serum fructosamine levels in pregnant women were lower than those in non-pregnant subjects. Serum fructosamine measurement is not a sufficiently sensitive test for diagnosis of gestational diabetes.
测定了孕期（妊娠28周）女性的血清果糖胺水平。这些女性（n = 99）还参与了口服葡萄糖耐量试验（OGTT），服用75g液体葡萄糖负荷，以确定其葡萄糖耐量。在妊娠32周时，其中79人重复进行了口服葡萄糖耐量试验和果糖胺测量。结果显示，葡萄糖耐量正常的孕妇（2.20±0.19 mmol/l，n = 76）在妊娠28周和32周时的果糖胺水平与葡萄糖不耐受（妊娠期糖尿病：2.19±0.22 mmol/l，n = 23）的孕妇相比，无统计学差异。然而，孕妇的血清果糖胺水平低于非孕妇。血清果糖胺测量对妊娠期糖尿病的诊断不是一项足够敏感的检测。
