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[HIV感染与老年人]

[HIV infection and the elderly].

作者信息

Major K, Clerc O, Rochat S, Cavassini M, Büla C

机构信息

Service de gériatrie et de réadaptation gériatrique, CHUV, Lausanne.

出版信息

Rev Med Suisse. 2011 Nov 9;7(316):2170, 2172-5.

Abstract

HIV infection is becoming a chronic disease, due to decreased mortality induced by the introduction of combined antiviral treatments. The HIV positive population is aging progressively. HIV infection in the elderly has certain specificities, including a late initial diagnosis, a less marked immune response to treatment and the potential association of multiple comorbidities associated with HIV infection and aging. These factors may affect the quality of life of elderly patients and ultimately lead to increased functional dependence. Screening and specific treatment of comorbidities associated with HIV and aging are particularly recommended.

摘要

由于联合抗病毒治疗的引入降低了死亡率,艾滋病毒感染正逐渐成为一种慢性病。艾滋病毒阳性人群正在逐渐老龄化。老年人感染艾滋病毒有一些特定情况,包括初始诊断较晚、对治疗的免疫反应不太明显,以及与艾滋病毒感染和老龄化相关的多种合并症的潜在关联。这些因素可能会影响老年患者的生活质量,并最终导致功能依赖增加。特别建议对与艾滋病毒和老龄化相关的合并症进行筛查和针对性治疗。

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